Evidence map›Paper›PMID 32899460›Full record

ArticleNutrients2020

Vitamin D Receptor Polymorphisms in Sex-Frailty Paradox.

Beatrice Arosio, Franca Rosa Guerini, Andrea Saul Costa, Alessandra Dicitore, Evelyn Ferri, Daniela Mari, Erminio Torresani, Mario Clerici, Matteo Cesari, Giovanni Vitale

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Inflammaging and the sex-frailty paradox.Aging clinical and experimental research · 2025
    Article
  3. Article
  4. Potential role of vitamin D levels in amyotrophic lateral sclerosis cognitive impairment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Beatrice ArosioGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-0615-3580
Franca Rosa GueriniIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy.ORCID 0000-0001-9461-5927
Andrea Saul CostaIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy.
Alessandra DicitoreLaboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Istituto Auxologico Italiano, IRCCS, 20095 Cusano Milanino, Italy.
Evelyn FerriGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Daniela MariLaboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Istituto Auxologico Italiano, IRCCS, 20095 Cusano Milanino, Italy.
Erminio TorresaniLaboratorio Analisi Cliniche Centro di Ricerche e Tecnologie Biomediche, Istituto Auxologico Italiano, IRCCS, 20095 Cusano Milanino, Italy.
Mario ClericiIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy.
Matteo CesariGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Giovanni VitaleDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
University of Milan · ITIRCCS Istituto Auxologico Italiano · ITDon Carlo Gnocchi Foundation · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

Istituto Auxologico Italiano 05C621_2016Ministero della Salute RC2019Università degli Studi di Milano PSR LINEA 2 2016 and 2019
6 · The paper itself

Abstract

The "male-female health-survival paradox" evidences that the survival advantage observed in women is linked to higher rates of disability and poor health status compared to men, a phenomenon also called the "sex-frailty paradox". The depletion of vitamin D seems to play a role in the fragilization of old persons, and genetic polymorphisms of the

Indexed as

Health Status IndicatorsSex FactorsAgedAged, 80 and overAllelesCalciumFemaleFrail ElderlyFrailtyGenetic Predisposition to DiseaseGenotypeHumansItalyMaleMiddle AgedParathyroid Hormone25-hydroxyvitamin DCalciumParathyroid HormonePhosphorusReceptors, CalcitriolVDR protein, humanVitamin Dagingfrailtyvitamin Dvitamin D receptor

Identifiers

PMID32899460
PMCPMC7551757
OpenAlexW3083175268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.