Evidence map›Paper›PMID 32899448›Full record

ArticleInternational journal of molecular sciences2020

Endothelial Jagged1 Antagonizes Dll4/Notch Signaling in Decidual Angiogenesis during Early Mouse Pregnancy.

Nicole M Marchetto, Salma Begum, Tracy Wu, Valerie O'Besso, Christina C Yarborough, Nuriban Valero-Pacheco, Aimee M Beaulieu, Jan K Kitajewski, Carrie J Shawber, Nataki C Douglas

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Signaling via retinoic acid receptors mediates decidual angiogenesis in mice and human stromal cell decidualization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Maternal IL-33 critically regulates tissue remodeling and type 2 immune responses in the uterus during early pregnancy in mice.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. [JAG1 promotes migration, invasion, and adhesion of triple-negative breast cancer cells by promoting angiogenesis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Notch signaling in reproduction.Trends in endocrinology and metabolism: TEM · 2021
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nicole M MarchettoDepartment of Obstetrics, Gynecology and Reproductive Health, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Salma BegumDepartment of Obstetrics, Gynecology and Reproductive Health, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Tracy WuDepartment of Obstetrics, Gynecology and Reproductive Health, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Valerie O'BessoRutgers New Jersey Medical School, Newark, NJ 07103, USA.
Christina C YarboroughSchool of Graduate Studies, Rutgers Biomedical and Health Sciences, Newark, NJ 07103, USA.
Nuriban Valero-PachecoDepartment of Microbiology, Biochemistry, and Molecular Genetics, Rutgers Biomedical and Health Sciences, Newark, NJ 07103, USA.ORCID 0000-0001-6091-6043
Aimee M BeaulieuDepartment of Microbiology, Biochemistry, and Molecular Genetics, Rutgers Biomedical and Health Sciences, Newark, NJ 07103, USA.ORCID 0000-0002-7301-0002
Jan K KitajewskiDepartment of Physiology & Biophysics, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-4660-593X
Carrie J ShawberDepartment of Obstetrics and Gynecology, Division of Reproductive Sciences, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Nataki C DouglasDepartment of Obstetrics, Gynecology and Reproductive Health, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.ORCID 0000-0001-8443-8875
Rutgers, The State University of New Jersey · USColumbia University · USUniversity of Illinois Chicago · US

Funding

Notch in Angiogenesis and Vascular BiologyR01HL112626 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jan K. Kitajewski · 2012 to 2026
$6.3M
Role of angiogenic Notch in uterine decidualization and placentationR01HL127013 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI DOUGLAS, NATAKI C · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL112626NHLBI NIH HHS R01 HL127013NIH HHS R01HL127013
6 · The paper itself

Abstract

Maternal spiral arteries and newly formed decidual capillaries support embryonic development prior to placentation. Previous studies demonstrated that Notch signaling is active in endothelial cells of both decidual capillaries and spiral arteries, however the role of Notch signaling in physiologic decidual angiogenesis and maintenance of the decidual vasculature in early mouse pregnancy has not yet been fully elucidated. We used the

Indexed as

AnimalsCalcium-Binding ProteinsCell ProliferationDeciduaEmbryo ImplantationEmbryonic DevelopmentEndometriumEndothelial CellsFemaleIntracellular Signaling Peptides and ProteinsJagged-1 ProteinMembrane ProteinsMiceMice, Inbred C57BLMorphogenesisNeovascularization, PathologicCalcium-Binding Proteinsdelta proteinIntracellular Signaling Peptides and ProteinsJagged-1 ProteinMembrane ProteinsReceptors, NotchVascular Endothelial Growth Factor Receptor-2angiogenesiscapillariesdeciduaDll4endothelial cellsJag1Notchspiral arteries

Identifiers

PMID32899448
PMCPMC7554752
OpenAlexW3083097593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.