Evidence map›Paper›PMID 32899428›Full record

ArticleInternational journal of molecular sciences2020

Role of the Transcription Factor Yin Yang 1 and Its Selectively Identified Target Survivin in High-Grade B-Cells Non-Hodgkin Lymphomas: Potential Diagnostic and Therapeutic Targets.

Silvia Vivarelli, Luca Falzone, Giovanni Ligresti, Saverio Candido, Adriana Garozzo, Gaetano Giuseppe Magro, Benjamin Bonavida, Massimo Libra

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Transcription Factors in Cancer.International journal of molecular sciences · 2022
    Article
  6. Article
  7. Article
  8. YY1 Silencing Induces 5-Fluorouracil-Resistance andInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Silvia VivarelliLaboratory of Translational Oncology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Luca FalzoneEpidemiology Unit, IRCCS Istituto Nazionale Tumori 'Fondazione G. Pascale', 80131 Naples, Italy.ORCID 0000-0001-7349-6826
Giovanni LigrestiLaboratory of Translational Oncology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Saverio CandidoLaboratory of Translational Oncology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Adriana GarozzoResearch Center for Prevention, Diagnosis and Treatment of Cancer, University of Catania, 95123 Catania, Italy.
Gaetano Giuseppe MagroResearch Center for Prevention, Diagnosis and Treatment of Cancer, University of Catania, 95123 Catania, Italy.
Benjamin BonavidaDepartment of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Massimo LibraLaboratory of Translational Oncology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-7232-7737
University of Catania · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of California, Los Angeles · US

Funding

University of Catania Linea di Intervento 2 2016-2018 Linea di Intervento 2 2016-2018, Identification of cancer driver genes for novel diagnostic and therapeutic strategies
6 · The paper itself

Abstract

B-cell non-Hodgkin lymphomas (B-NHLs) are often characterized by the development of resistance to chemotherapeutic drugs and/or relapse. During drug-induced apoptosis, Yin Yang 1 (

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsApoptosisBiomarkers, TumorCell ProliferationDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticGene SilencingHumansLymphoma, B-CellSurvivinTumor Cells, CulturedYY1 Transcription FactorBiomarkers, TumorBIRC5 protein, humanSurvivinYY1 protein, humanYY1 Transcription FactorapoptosisB-cell non-Hodgkin lymphomaBIRC5/survivinBurkitt’s lymphomachemotherapyYin Yang 1

Identifiers

PMID32899428
PMCPMC7504013
OpenAlexW3082975221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.