Evidence map›Paper›PMID 32899294›Full record

ArticleCancers2020

Pre- and Post-Zygotic TP53 De Novo Mutations in SHH-Medulloblastoma.

Jacopo Azzollini, Elisabetta Schiavello, Francesca Romana Buttarelli, Carlo Alfredo Clerici, Laura Tizzoni, Giovanna De Vecchi, Fabio Capra, Federica Pisati, Veronica Biassoni, Letterio Runza and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Jacopo AzzolliniUnit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.ORCID 0000-0002-9364-9778
Elisabetta SchiavelloPediatric Oncology Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.ORCID 0000-0002-8049-7445
Francesca Romana ButtarelliDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Roma, Italy.
Carlo Alfredo ClericiDepartment of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.
Laura TizzoniCancer Genetics Test Laboratory, Cogentech s.r.l. Società Benefit a Socio Unico, 20139 Milan, Italy.
Giovanna De VecchiCancer Genetics Test Laboratory, Cogentech s.r.l. Società Benefit a Socio Unico, 20139 Milan, Italy.
Fabio CapraCancer Genetics Test Laboratory, Cogentech s.r.l. Società Benefit a Socio Unico, 20139 Milan, Italy.
Federica PisatiHistopathology Unit, Cogentech s.r.l. Società Benefit a Socio Unico, 20139 Milan, Italy.
Veronica BiassoniPediatric Oncology Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.
Letterio RunzaDivision of Pathology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Giorgio CarrabbaDivision of Neurosurgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-0170-0653
Felice GiangasperoDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Roma, Italy.
Maura MassiminoPediatric Oncology Unit, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.ORCID 0000-0002-5506-2001
Valeria PensottiCancer Genetics Test Laboratory, Cogentech s.r.l. Società Benefit a Socio Unico, 20139 Milan, Italy.ORCID 0000-0003-1076-359X
Siranoush ManoukianUnit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.
Fondazione IRCCS Istituto Nazionale dei Tumori · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIstituto Neurologico Mediterraneo · ITSapienza University of Rome · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Li-Fraumeni syndrome (LFS) is an autosomal dominant disorder caused by mutations in the

Indexed as

de novo mutationLi-Fraumeni syndromemedulloblastomasomatic mosaicismTP53

Identifiers

PMID32899294
PMCPMC7564492
OpenAlexW3081824375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.