Evidence map›Paper›PMID 32899218›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

In Vitro Selective Growth-Inhibitory Activities of Phytochemicals, Synthetic Phytochemical Analogs, and Antibiotics against Diarrheagenic/Probiotic Bacteria and Cancer/Normal Intestinal Cells.

Tomas Kudera, Ivo Doskocil, Hana Salmonova, Miloslav Petrtyl, Eva Skrivanova, Ladislav Kokoska

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Cross-resistance between halquinol and antibiotics of importance in human and animal health.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  4. Can Nature Overcome Invasive Gastrointestinal Infections?International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Microbiology spectrum · 2022
    Article
  9. Special Issue "Novel Antibacterial Agents".Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Frontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomas KuderaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.
Ivo DoskocilDepartment of Microbiology, Nutrition and Dietetics, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.ORCID 0000-0002-7373-1360
Hana SalmonovaDepartment of Microbiology, Nutrition and Dietetics, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.ORCID 0000-0002-6839-9180
Miloslav PetrtylDepartment of Zoology and Fisheries, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.
Eva SkrivanovaDepartment of Microbiology, Nutrition and Dietetics, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.
Ladislav KokoskaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, 16500 Praha-Suchdol, Czech Republic.
Czech University of Life Sciences Prague · CZ

Funding

Česká Zemědělská Univerzita v Praze IGA 20195003European Regional Development Fund CZ.02.1.01/0.0/0.0/16_019/0000845
6 · The paper itself

Abstract

A desirable attribute of novel antimicrobial agents for bacterial diarrhea is decreased toxicity toward host intestinal microbiota. In addition, gut dysbiosis is associated with an increased risk of developing intestinal cancer. In this study, the selective growth-inhibitory activities of ten phytochemicals and their synthetic analogs (berberine, bismuth subsalicylate, ferron, 8-hydroxyquinoline, chloroxine, nitroxoline, salicylic acid, sanguinarine, tannic acid, and zinc pyrithione), as well as those of six commercial antibiotics (ceftriaxone, ciprofloxacin, chloramphenicol, metronidazole, tetracycline, and vancomycin) against 21 intestinal pathogenic/probiotic (e.g.,

Indexed as

antibacterialanticancerdiarrheaplant compoundsselectivity

Identifiers

PMID32899218
PMCPMC7558399
OpenAlexW3082201801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.