ArticleEuropean journal of dentistry2021
Effect of Tricalcium Silicate on Direct Pulp Capping: Experimental Study in Rats.
Article in European journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Histological evaluation of pulpal healing following direct pulp capping with polytetrafluoroethylene or melatonin, with or without adjunctive low-level laser therapy in Wistar rat molars.Scientific reports · 2026Article
- The Function and Role of Intercellular Adhesion Molecule 2 in Dental Pulp Cells and Tissue.International journal of molecular sciences · 2025Article
- Metallomic characterization of induced periapical lesions-In vivo study.International endodontic journal · 2025Article
- Selective caries removal and management of exposed pulp in fully developed and immature teeth with reversible pulpitis: a questionnaire-based study in Greece.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Effect of Vital Pulp Therapy Biomaterials on Tooth Discolouration: A Review of the Literature.International journal of biomaterials · 2025Review
- GelMA/TCP nanocomposite scaffold for vital pulp therapy.Acta biomaterialia · 2024Article
- Influence of Lithium- and Zinc-Containing Bioactive Glasses on Pulpal Regeneration.European journal of dentistry · 2023Article
- Experimental study of dexamethasone-loaded hollow hydroxyapatite microspheres applied to direct pulp capping of rat molars.Frontiers in endocrinology · 2023Article
- A Compilation of Study Models for Dental Pulp Regeneration.International journal of molecular sciences · 2022Review
- Involvement of M1/M2 Macrophage Polarization in Reparative Dentin Formation.Life (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesConduct a histological comparison of the pulp response to different materials, with a focus on the continuity and morphology of the mineralized barrier after direct pulp capping. MATERIALS AND
methodsOne hundred and eight maxillary first molars of 54 Wistar rats were subject to direct pulp capping and divided into three groups according to the materials used: calcium hydroxide (CH), mineral trioxide aggregate (MTA), and Biodentine. All cavities were sealed, and the animals were euthanized at 7, 14, and 21 days. Descriptive histological evaluation of the inflammation and formation of the mineralized barrier was performed. STATISTICAL ANALYSIS: Statistical analyses were performed using the Kruskal-Wallis test, which was complemented by the Dunn test; differences with
resultsThe results showed that MTA and Biodentine elicited less intense inflammatory reactions than CH. With respect to the formation and quality of the dentin barrier formed, differences were observed at 21 days between the analyzed groups; the best results being obtained following treatment with MTA and Biodentine.
conclusionMTA and Biodentine induced formation of a more continuous and uniform mineralized barrier with less intense pulp response than CH.
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Registered trials
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