Evidence map›Paper›PMID 32898797›Full record

ArticleThe Science of the total environment2021

A case-control analysis of traceback investigations for Vibrio parahaemolyticus infections (vibriosis) and pre-harvest environmental conditions in Washington State, 2013-2018.

Benjamin J K Davis, Anne E Corrigan, Zhe Sun, Erika Atherly, Angelo DePaola, Frank C Curriero

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Science of the total environment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Environmental Factors Associated with Incidence and Distribution ofbioRxiv : the preprint server for biology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Microbial Profiles of Retail Pacific Oysters (Frontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Benjamin J K DavisSpatial Science for Public Health Center, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 627 N. Washington Street, Baltimore, MD 21205, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA; Center for Chemical Regulation and Food Safety, Exponent, Inc., 1105 Connective Avenue #1100, Washington, DC 20036, USA.
Anne E CorriganSpatial Science for Public Health Center, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 627 N. Washington Street, Baltimore, MD 21205, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Zhe SunDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Erika AtherlyOffice of Environmental Health & Safety, Division of Environmental Public Health, Washington State Department of Health, Olympia, WA, USA.
Angelo DePaolaAngelo DePaola Consulting, Coden, AL, USA.
Frank C CurrieroSpatial Science for Public Health Center, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 627 N. Washington Street, Baltimore, MD 21205, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: fcurriero@jhu.edu.
Johns Hopkins University · USWashington State Department of Health · US

Funding

Characterizing the Spatial Temporal Dynamics and Human Health Risks of Vibrio parahaemolyticus Bacteria in Estuarine EnvironmentsR01AI123931 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CURRIERO, FRANK · 2016 to 2020
$2.7M
NIAID NIH HHS R01 AI123931
6 · The paper itself

Abstract

backgroundVibrio parahaemolyticus is a major cause of seafood-borne illness. It is naturally prevalent in brackish waters and accumulates in shellfish. Vibriosis cases are rising globally, likely due to rising temperatures.

objectivesTo identify associations between vibriosis in Washington State and pre-harvest environmental and V. parahaemolyticus genetic measurements sampled from shellfish.

methodsSuccessful vibriosis traceback investigations were spatiotemporally matched to routine intertidal oyster (Crassostrea gigas) sampling events, which included measurements of temperature, salinity, and V. parahaemolyticus genetic targets (thermolabile hemolysin: tlh; thermostable direct hemolysin: tdh; thermostable direct-related hemolysin: trh). Unmatched sampling events were treated as controls. Associations were evaluated using logistic regression models.

resultsSystematic differences were observed across Washington harvesting zones. These included positive associations between the odds of vibriosis and all three genetic targets in South Puget Sound, with a large odds ratio (OR) = 13.0 (95% CI: 1.5, 115.0) for a 1-log DISCUSSION: The zonal variation in associations indicates unique pathogenic strain prominence, suggesting tdh+/trh+ strains in South Puget Sound, such as the O4:K12 serotype, and tdh+/trh- strains in the coastal bays. The temperature discrepancy between water and oyster tissue suggests that South Puget Sound pathogenic strains flourish with exposure to relatively warm air during low tide. These findings identify new ecological risk factors for vibriosis in Washington State that can be used in future prevention efforts.

Indexed as

Vibrio InfectionsVibrio parahaemolyticusAnimalsBacterial ProteinsHemolysin ProteinsShellfishWashingtonBacterial ProteinsHemolysin ProteinsEnvironmental epidemiologyInfectious diseasesThermolabile hemolysinThermostable direct hemolysinThermostable direct-related hemolysinWater temperature

Identifiers

PMID32898797
PMCPMC7674187
OpenAlexW3048726154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.