Evidence map›Paper›PMID 32898765›Full record

ReviewCurrent opinion in insect science2020

The Drosophila midgut and the systemic coordination of lipid-dependent energy homeostasis.

Xiao Zhao, Jason Karpac

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in insect science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Lipids in Insect Reproduction: Where, How, and Why.Advances in experimental medicine and biology · 2026
    Review
  3. Lipophorin: The Lipid Shuttle.Advances in experimental medicine and biology · 2026
    Review
  4. Dietary Lipids and Their Metabolism in the Midgut.Advances in experimental medicine and biology · 2026
    Review
  5. Transcriptional Control of Lipid Metabolism.Advances in experimental medicine and biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A soil fungus confers plant resistance against a phytophagous insect by disrupting the symbiotic role of its gut microbiota.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Markers and mechanisms of death inFrontiers in aging · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiao ZhaoDept. of Molecular and Cellular Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Jason KarpacDept. of Molecular and Cellular Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA. Electronic address: karpac@tamu.edu.
Texas A&M Health Science Center · US

Funding

Foxo/NFkB Interactions in the Regulation of Metabolic HomeostasisR01DK108930 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI KARPAC, JASON S · 2016 to 2020
$1.7M
NIDDK NIH HHS R01 DK108930
6 · The paper itself

Abstract

The evolution of complex organ systems in metazoans has dictated that the maintenance of energy homeostasis requires coordinating local and systemic energy demands between organs with specialized functions. The gastrointestinal tract is one of many organs that is indispensable for the systemic coordination of energy substrate uptake, storage, and usage, and the spatial organization of this organ (i.e. proximity to other metabolic organs) within a complex body plan underlies its role in organ crosstalk. Studies of various arthropod intestines, and in particular insects, have shed light on the evolution and function of the gastrointestinal tract in the maintenance of energy homeostasis. This brief review focuses on studies and theories derived from the insect intestine (particularly the midgut) of adult Drosophila melanogaster to inform on the how, what, and why of the gastrointestinal tract in the systemic regulation of lipids, the most common form of stored energy in insects.

Indexed as

Lipid MetabolismAnimalsDrosophila melanogasterEnergy MetabolismGastrointestinal TractHomeostasis

Identifiers

PMID32898765
PMCPMC7669600
OpenAlexW3049152190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.