Evidence map›Paper›PMID 32898280›Full record

ArticleJournal of the American Geriatrics Society2020

Preoperative Depressive Symptoms Associated with Poor Functional Recovery after Surgery.

Victoria L Tang, Irena Cenzer, Charles E McCulloch, Emily Finlayson, Zara Cooper, Molly Silvestrini, Sarah Ngo, Eva M Schmitt, Sharon K Inouye

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Integrating Mental Health Into Surgical Care: A Qualitative Study of a Perioperative Mental Health Intervention.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
  4. Article
  5. Review
  6. Treating mental and social health: A call for alternative payment models in orthopaedic trauma.OTA international : the open access journal of orthopaedic trauma · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Victoria L TangDivision of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Irena CenzerDivision of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
Emily FinlaysonDepartment of Surgery, University of California, San Francisco, San Francisco, California, USA.
Zara CooperCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Molly SilvestriniDivision of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Sarah NgoDivision of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Eva M SchmittAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.
Sharon K InouyeAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.
University of California, San Francisco · USHebrew SeniorLife · USBrigham and Women's Hospital · USPublic Policy Institute of California · USSan Francisco VA Medical Center · US

Funding

The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2010 to 2022
$26.7M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KENNETH E. COVINSKY, R. Sean Morrison · 2020 to 2026
$17.7M
Development and Validation of a Delirium Severity ToolkitR01AG044518 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K., JONES, RICHARD N · 2014 to 2024
$7.3M
Supplement to Network for Investigation of Delirium across the U.S (NIDUS)R24AG054259 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2016 to 2020
$4.3M
Improving Outcomes of Older Adults with Psychosocial Vulnerability Undergoing Major SurgeryK76AG059931 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TANG, VICTORIA LAI-YEN · 2019 to 2023
$1.4M
K07 Leadership GrantK07AG041835 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2013 to 2017
$656k
Geriatric Factors and Outcomes after High Risk Surgery in Older AdultsR03AG056342 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TANG, VICTORIA LAI-YEN · 2017 to 2018
$238k
NCATS NIH HHS KL2 TR001870NIA NIH HHS K07 AG041835NIA NIH HHS K07AG041835NIA NIH HHS K76 AG059931NIA NIH HHS P01 AG031720NIA NIH HHS P01 AG066605NIA NIH HHS P30 AG044281NIA NIH HHS R01 AG044518NIA NIH HHS R01AG044518NIA NIH HHS R03 AG056342NIA NIH HHS R03AG056342NIA NIH HHS R24 AG054259NIA NIH HHS R24AG054259NIH HHS KL2TR001870NIH HHS P30AG044281
6 · The paper itself

Abstract

BACKGROUND/

objectivesDepression screening and treatment for older adults are recommended in Age-Friendly Health Systems. Few studies have evaluated the association between depressive symptoms and postoperative functioning. We aimed to determine the association between varying levels of depressive symptoms in the preoperative setting with postoperative functional recovery.

designProspective cohort study.

settingTwo academic hospitals in Boston, Massachusetts.

participantsSurgical patients aged 70 and older (N = 560). MEASUREMENTS: Participants were assessed preoperatively and 1 year postoperatively. Preoperative evaluation included the 15-item short-form Geriatric Depression Scale (GDS). Results were categorized as low (GDS = 0-1), moderate (2-5), or high (6-15) symptom burden. Primary outcome was 1-year instrumental activities of daily living functional decline. Secondary outcomes included hospital stay longer than 5 days, discharge to post-acute care (PAC) facility, and readmission within 30 days.

resultsMean participant age was 76.6 ± 5 years, 58% were women, 81% underwent an orthopedic operation, 13% gastrointestinal, 6% vascular; 13% had functional decline at 1 year after their operation (by symptom burden: low = 5.5%; moderate = 14.8%, and high = 38.6%). After adjusting for age, sex, and comorbidity, those with moderate or high depressive symptoms demonstrated greater odds of functional decline at 1 year compared with those with a low symptom burden (moderate: adjusted odds ratio [AOR] = 2.7; 95% confidence interval [CI] = 1.3-5.3; high: AOR = 9.3; 95% CI = 4.2-20.6), discharge to PAC facility (moderate: AOR = 1.7; 95%CI = 1.2-2.6; high: AOR = 2.7; 95% CI = 1.4-5.1) but demonstrated no significant association with 30-day readmission or hospital length of stay longer than 5 days.

conclusionGreater burden of preoperative depressive symptoms is associated with increased likelihood of functional decline at 1 year after surgery and of discharge to PAC facility. Preoperative assessment of the burden of depressive symptoms in older adults undergoing elective surgery may be helpful in identifying patients at high risk of poor outcomes.

Indexed as

Activities of Daily LivingElective Surgical ProceduresRecovery of FunctionAgedBostonComorbidityDepressionFemaleHumansMaleMassachusettsOrthopedic ProceduresPatient DischargePatient ReadmissionPostoperative PeriodPreoperative Caredepressionfunctional recoveryolder adultssurgery outcomes

Identifiers

PMID32898280
PMCPMC7744402
OpenAlexW3085171257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.