ArticleMenopause (New York, N.Y.)2020
Age at menarche and cardiovascular health: results from the NHANES 1999-2016.
Article in Menopause (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Age at menarche and blood pressure in late adolescence: the role of body adiposity in a Brazilian birth cohort.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026Article
- Age at Menarche and Its Association with Cardiovascular Disease in Women with Childhood-Onset Type 1 Diabetes (T1D).Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Maternal time interval between menarche and childbirth is associated with daughter's age at menarche.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Mother's age at menarche is associated with odds of preterm delivery: A case-control study.BJOG : an international journal of obstetrics and gynaecology · 2024Article
- Article
- Age at menarche, type 2 diabetes and cardiovascular disease complications in US women aged under 65 years: NHANES 1999-2018.BMJ nutrition, prevention & health · 2023Article
- An affordable approach to classifying type 2 diabetes based on fasting plasma glucose, TyG index and BMI: a retrospective cohort study of NHANES Data from 1988 to 2014.Diabetology & metabolic syndrome · 2022Article
- Validation of type 2 diabetes subgroups by simple clinical parameters: a retrospective cohort study of NHANES data from 1999 to 2014.BMJ open · 2022Article
- Age at menarche and ischemic heart disease: An update mendelian randomization study.Frontiers in genetics · 2022Article
- Management of Ischemic Heart Disease in Pregnancy.Current atherosclerosis reports · 2021Review
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4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveCardiovascular disease is the leading cause of death among women. Early menarche has been associated with many cardiovascular disease risk factors, but little is known about its associations with cardiovascular health (CVH) as defined by Life's Simple 7 (LS7). We aim to examine the associations between age at menarche and CVH.
methodsData were obtained from the 1999-2016 National Health and Nutrition Examinations Survey (NHANES). CVH was assessed according to LS7 (ideal CVH: > 4 ideal CVH metrics, CVH score: ranging from 0 to 14). Weighted logistic regression was used after adjusting for sociodemographic factors. The interaction between age at menarche and age was also examined.
resultsAmong the 20,447 women included, 2,292 (11.2%) had ideal CVH. After adjusting for age, race/ethnicity, education, poverty income ratio, marital status, and birth year, significantly worse CVH was observed among women with early menarche (OR: 0.70, 95% CI: 0.60-0.82), and higher odds of ideal CVH were observed among those with late menarche (OR: 1.40, 95% CI: 1.21-1.62). Consistent results were observed for CVH score. Age significantly modifies the associations between age at menarche and CVH. Late menarche was significantly associated with ideal CVH among those aged 25-34 (OR: 1.64, 95% CI: 1.27-2.11) or 35-44 (OR: 1.73, 95% CI: 1.31-2.30), while the associations for early menarche were observed only among those aged 25-34 years (OR: 0.72, 95% CI: 0.53-0.97).
conclusionsOur findings suggested that early menarche is associated with worse CVH, especially among young women. Further efforts are warranted to confirm these findings.
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