Evidence map›Paper›PMID 32897856›Full record

ArticleeLife2020

A regulatory pathway that selectively up-regulates elongasome function in the absence of class A PBPs.

Yesha Patel, Heng Zhao, John D Helmann

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. ThebioRxiv : the preprint server for biology · 2025
    Article
  4. Staying in the loop to make ends meet: roles and regulation of GlmR inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Journal of bacteriology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Journal of bacteriology · 2024
    Article
  12. Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Mutations inmBio · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yesha PatelDepartment of Microbiology, Cornell University, Ithaca, United States.ORCID 0000-0001-9888-9888
Heng ZhaoDepartment of Microbiology, Cornell University, Ithaca, United States.ORCID 0000-0002-7322-5513
John D HelmannDepartment of Microbiology, Cornell University, Ithaca, United States.ORCID 0000-0002-3832-3249
Cornell University · US

Funding

Bacillus subtilis Stress ResponsesR35GM122461 · NIGMS · CORNELL UNIVERSITY · PI John D Helmann · 2017 to 2026
$7.6M
NIGMS NIH HHS R35 GM122461
6 · The paper itself

Abstract

Bacteria surround themselves with peptidoglycan, an adaptable enclosure that contributes to cell shape and stability. Peptidoglycan assembly relies on penicillin-binding proteins (PBPs) acting in concert with SEDS-family transglycosylases RodA and FtsW, which support cell elongation and division respectively. In

Indexed as

Gene Expression Regulation, BacterialBacillus subtilisBacterial ProteinsCell WallN-Acetylmuramoyl-L-alanine AmidasePenicillin-Binding ProteinsPeptidoglycanPeptidoglycan GlycosyltransferaseSigma FactorUp-RegulationBacterial ProteinsLytE protein, Bacillus subtilisN-Acetylmuramoyl-L-alanine AmidasePenicillin-Binding ProteinsPeptidoglycanPeptidoglycan GlycosyltransferaseSigma FactorantibioticB. subtiliscell wallelongasomegene regulationgeneticsgenomicspenicillin-binding proteinpeptidoglycan

Identifiers

PMID32897856
PMCPMC7478892
OpenAlexW3084115636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.