SynthesisNeuropsychology review2021
Procedural Learning in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer's Dementia: a Systematic Review and Meta-analysis.
Synthesis in Neuropsychology review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Motor Learning in Older Adults with Mild Cognitive Impairment: A Systematic Review.Neuropsychology review · 2026Pooled it
- 'Doing it together?' A dyadic qualitative study of perceptions, facilitators, barriers and expectations for physical activity in dementia.Age and ageing · 2026Article
- A Comprehensive Self-Medication Management System to Reduce Medication Errors Among People Living With Dementia: Mixed Methods Feasibility and Usability Study.JMIR human factors · 2026Article
- Prescribing Assistive Technology for Cognition to Support Aging in Place: OTs' Perspective.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2026Article
- Calibrating limitation features and dependence levels in basic activities of daily living among individuals with dementia: an item response theory-based analysis.BMC geriatrics · 2026Article
- Web-Based Application to Support Caregivers in the Use of Learning Optimization Methods: Participatory Action Research Study.JMIR aging · 2026Article
- Behavior change techniques in a care partner-assisted oral health intervention for people with mild dementia: a secondary mixed-methods analysis.Innovation in aging · 2026Article
- Predictors of transitions between normal cognition, cognitive impairment, and dementia in a longitudinal cohort.Journal of Alzheimer's disease : JAD · 2025Article
- Article
- Article
- Are board games useful for people with dementia? A preliminary study for a non-pharmacological intervention.Frontiers in psychology · 2025Article
- Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Early-Stage Alzheimer's Disease Affects Fast But Not Slow Adaptive Processes in Motor Learning.eNeuro · 2024Article
- Article
- Examining the Diagnostic Accuracy of a Novel Performance-Based Test for Alzheimer's Disease Screening.The journal of prevention of Alzheimer's disease · 2024Article
- Qualitative research concerning physiotherapy approaches to encourage physical activity in older adults with dementia.PloS one · 2023Article
- A framework for rehabilitation for older adults living with dementia.Archives of physiotherapy · 2022Article
- Practice effects in cognitive assessments three years later in non-carriers but not in symptom-free mutation carriers of autosomal-dominant Alzheimer's disease: Exemplifying procedural learning and memory?Frontiers in aging neuroscience · 2022Article
- Behavioral Interventions in Mild Cognitive Impairment (MCI): Lessons from a Multicomponent Program.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Caregivers' roles in preventing patients with severe Alzheimer's disease from becoming distracted during mealtimes: two case reports.Journal of physical therapy science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The notion that procedural learning and memory is spared in Alzheimer's disease (AD) has important implications for interventions aiming to build on intact cognitive functions. However, despite these clinical implications, there are mixed findings in the literature about whether or not procedural learning remains intact. This meta-analysis examines the standard mean difference of all published studies regarding procedural learning in AD dementia or amnestic Mild Cognitive Impairment (aMCI) compared to cognitively healthy older adults. Additionally, we conducted statistical equivalence analyses. Our systematic review showed that only a limited number of studies (k = 17) have compared procedural learning between individuals with aMCI or AD dementia and healthy controls. Our meta-analysis, which synthesized these studies, demonstrated that while procedural learning performance was not statistically equivalent between individuals with aMCI or AD dementia, and healthy older adults, the difference was clinically and statistically trivial. Although larger studies are needed, the present findings suggest that procedural learning does appear to remain spared in aMCI and AD dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.