Evidence map›Paper›PMID 32897210›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Cholinergic anti-inflammatory pathway plays negative regulatory role in early inflammatory and immune responses in septic rats].

Hongbing Li, Yuan Li, Wushi Wang, Zongshuang Peng, Fang Wu

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Research Advances in the Pathogenesis of Sepsis-Associated Encephalopathy.International journal of molecular sciences · 2026
    Review
  2. From Glycocalyx Shedding to Microvascular Collapse in Sepsis: Endothelial Pathophysiology, Organ Dysfunction, and Mechanistic Biomarkers.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  3. Article
  4. Article
  5. The Regulation Effect ofMediators of inflammation · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hongbing LiDepartment of Emergency Medicine, Guiyang First People's Hospital, Guiyang 550002, China.
Yuan LiDepartment of Emergency Medicine, Guiyang First People's Hospital, Guiyang 550002, China.
Wushi WangDepartment of Emergency Medicine, Guiyang First People's Hospital, Guiyang 550002, China.
Zongshuang PengDepartment of Emergency Medicine, Guiyang First People's Hospital, Guiyang 550002, China.
Fang WuDepartment of Emergency Medicine, Guiyang First People's Hospital, Guiyang 550002, China.
The First People's Hospital of Guiyang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of cholinergic anti-inflammatory pathway (CAP) in neuro-regulation of inflammatory and immune response in the early stage of sepsis.

methodsSixty-four SD rats were randomly divided into control Group (

resultsCompared with the control rats, the septic rats had significantly increased MSS scores and lowered HRV indexes (SDNN, RMSSD, HF, SD1, and SD2;

conclusionsCAP plays negative regulatory role in early inflammatory and immune response to sepsis, and some of the HRV indicators can well reflect the regulatory effect of CAP on inflammation and immunity in the septic rats.

Indexed as

NeuroimmunomodulationSepsisAnimalsDisease Models, AnimalMiceRatsRats, Sprague-DawleyT-Lymphocytes, Regulatorycholinergic anti-inflammatory pathwayheart rate variabilityimmune balancepro-inflammatory cytokinessepsis

Identifiers

PMID32897210
PMCPMC7277322
OpenAlexW3084269247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.