Evidence map›Paper›PMID 32897053›Full record

ArticleAnalytical chemistry2020

Serge D Zemerov, Benjamin W Roose, Kelsey L Farenhem, Zhuangyu Zhao, Madison A Stringer, Aaron R Goldman, David W Speicher, Ivan J Dmochowski

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. UltrasensitiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Serge D ZemerovDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Benjamin W RooseDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Kelsey L FarenhemDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-5747-7999
Zhuangyu ZhaoDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Madison A StringerDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Aaron R GoldmanProteomics and Metabolomics Facility, The Wistar Institute, Philadelphia, Pennsylvania 19104, United States.
David W SpeicherProteomics and Metabolomics Facility, The Wistar Institute, Philadelphia, Pennsylvania 19104, United States.
Ivan J DmochowskiDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0001-7162-1347
University of Pennsylvania · USThe Wistar Institute · US

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
Designer Molecular Probes for Biomedical ApplicationsR35GM131907 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ivan Julian Dmochowski · 2019 to 2026
$4.7M
Structure-Based Design of Xe-129 NMR Biosensors for Multiplexed Cancer DetectionR01GM097478 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2011 to 2018
$3.1M
Advancing Cancer Research through Comprehensive Proteomics and Metabolomics AnalysesR50CA221838 · NCI · WISTAR INSTITUTE · PI Hsin-Yao Tang · 2017 to 2026
$2.1M
Purchase of a Q Exactive HF mass spectrometer system for metabolomicsS10OD023586 · OD · WISTAR INSTITUTE · PI SPEICHER, DAVID W. · 2017 to 2017
$600k
NCI NIH HHS P30 CA010815NCI NIH HHS R50 CA221838NIGMS NIH HHS R01 GM097478NIGMS NIH HHS R35 GM131907NIH HHS S10 OD023586
6 · The paper itself

Abstract

Dysregulation of cellular ribose uptake can be indicative of metabolic abnormalities or tumorigenesis. However, analytical methods are currently limited for quantifying ribose concentration in complex biological samples. Here, we utilize the highly specific recognition of ribose by ribose-binding protein (RBP) to develop a single-protein ribose sensor detectable

Indexed as

Escherichia coli ProteinsHumansMagnetic Resonance SpectroscopyModels, MolecularPeriplasmic Binding ProteinsRiboseXenon IsotopesEscherichia coli ProteinsPeriplasmic Binding ProteinsRbsB protein, E coliRiboseXenon Isotopes

Identifiers

PMID32897053
PMCPMC7649717
OpenAlexW3083772784

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.