Evidence map›Paper›PMID 32896111›Full record

ArticleNeuropsychopharmacology reports2020

Risk factors for the onset of dependence and chronic psychosis due to cannabis use: Survey of patients with cannabis-related psychiatric disorders.

Toshihiko Matsumoto, Toshitaka Kawabata, Kyoji Okita, Yuko Tanibuchi, Daisuke Funada, Maki Murakami, Takashi Usami, Rie Yokoyama, Nobuya Naruse, Yuzo Aikawa and 7 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Neuropsychopharmacology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 3 countries.

Toshihiko MatsumotoDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.ORCID 0000-0002-7076-2161
Toshitaka KawabataDepartment of Psychiatry, Kyoto Prefectural Rakunan Hospital, Uji, Japan.
Kyoji OkitaDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.
Yuko TanibuchiDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.ORCID 0000-0002-1690-6793
Daisuke FunadaDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.ORCID 0000-0001-5228-4699
Maki MurakamiDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.
Takashi UsamiDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.
Rie YokoyamaDepartment of Psychiatry, Kaisei Hospital, Kasama, Japan.
Nobuya NaruseDepartment of Psychiatry, Saitama Prefectural Psychiatric Hospital, Saitama, Japan.
Yuzo AikawaDepartment of Psychiatry, Saitama Prefectural Psychiatric Hospital, Saitama, Japan.
Aizo FurukawaDepartment of Psychiatry, Seimei Hospital, Fukuoka, Japan.
Chie KomatsuzakiDepartment of Psychiatry, Ibaraki Prefectural Medical Center of Psychiatry, Kasama, Japan.
Nozomu HashimotoDepartment of Psychiatry, Okayama Psychiatric Medical Center, Okayama, Japan.
Osamu FujitaDepartment of Psychiatry, Osaka Psychiatric Medical Center, Osaka, Japan.
Aiko UmemotoDepartment of Psychiatry, Osaka Psychiatric Medical Center, Osaka, Japan.
Ariyuki KagayaKONUMA Memorial Institute of Addiction and Mental Health, Senogawa Hospital, Hiroshima, Japan.
Takuya ShimaneDepartment of Drug Dependence Research, National Center of Neurology and Psychiatry, National Institute of Mental Health, Kodaira, Japan.ORCID 0000-0001-8906-6230
National Center of Neurology and Psychiatry · JPOsaka Medical and Pharmaceutical University · JPSaitama Prefectural University · JPConnecticut Department of Mental Health and Addiction Services · USFukuoka Hospital · JPIbaraki Prefectural Central Hospital · JPKobe Kaisei Hospital · JPKyoto Prefectural Rakuhoku High School · JPOkayama Psychiatric Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of the current study was to identify risk factors that affect the onset of dependence and chronic psychosis due to cannabis use.

methodsWe examined clinical genetic factors, psychiatric disorders prior to cannabis use, starting age of cannabis use, duration and frequency of cannabis use, types of cannabis products used, combined use of other psychoactive substances, and the psychiatric diagnosis of 71 patients with cannabis-related psychiatric disorders who underwent treatment at nine mental health hospitals in Japan. Information was collected from cross-sectional interview surveys conducted by each patient's attending psychiatrist.

resultsFor the diagnosis of dependence syndrome due to the use of cannabis, we found associations with the number of years of cannabis use and the use of cannabis products with a high Δ9-tetrahydrocannabinol (THC) content. However, we found no association between diagnosis of residual and late-onset psychotic disorders and clinical genetic factors, presence of preceding psychiatric disorders, duration and frequency of cannabis use, starting age of cannabis use, or combined use of other psychoactive substances; an association was found only for the absence of use of cannabis products other than dried cannabis.

conclusionThe onset of cannabis dependence was related to long-term cannabis use and the use of cannabis products with a high THC content. However, chronic psychosis was not associated with total THC intake or psychiatric vulnerability. Thus, unknown factors appear to be involved in the onset of chronic psychosis.

Indexed as

Surveys and QuestionnairesAdultAge FactorsChronic DiseaseFemaleHumansJapanMaleMarijuana AbuseMiddle AgedPsychotic DisordersRisk Factorscannabischronic psychosisdependencerisk factoruse disorder

Identifiers

PMID32896111
PMCPMC7722680
OpenAlexW3083951532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.