Evidence map›Paper›PMID 32895867›Full record

ReviewPharmaceutical research2020

Highlights in Mesoporous Silica Nanoparticles as a Multifunctional Controlled Drug Delivery Nanoplatform for Infectious Diseases Treatment.

Gabriela Corrêa Carvalho, Rafael Miguel Sábio, Tais de Cássia Ribeiro, Andreia Sofia Monteiro, Daniela Vassalo Pereira, Sidney José Lima Ribeiro, Marlus Chorilli

Open access · bronzeAbstract readReview
In one paragraph

Review in Pharmaceutical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 108 citations in OpenAlex.

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  17. Organically Modified Mesoporous Silica Nanoparticles against Bacterial Resistance.Chemistry of materials : a publication of the American Chemical Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gabriela Corrêa CarvalhoSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, 14800-903, Brazil.
Rafael Miguel SábioSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, 14800-903, Brazil. rafaelmsabio@gmail.com.ORCID http://orcid.org/0000-0002-3852-2184
Tais de Cássia RibeiroSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, 14800-903, Brazil.
Andreia Sofia MonteiroInstitute of Chemistry, São Paulo State University (UNESP), Araraquara, 14800-060, Brazil.
Daniela Vassalo PereiraInstitute of Chemistry, São Paulo State University (UNESP), Araraquara, 14800-060, Brazil.
Sidney José Lima RibeiroInstitute of Chemistry, São Paulo State University (UNESP), Araraquara, 14800-060, Brazil.
Marlus ChorilliSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, 14800-903, Brazil.
Universidade Estadual Paulista (Unesp) · BRCentro Universitário de Araraquara · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases are a major global concern being responsible for high morbidity and mortality mainly due to the development and enhancement of multidrug-resistant microorganisms exposing the fragility of medicines and vaccines commonly used to these treatments. Taking into account the scarcity of effective formulation to treat infectious diseases, nanotechnology offers a vast possibility of ground-breaking platforms to design new treatment through smart nanostructures for drug delivery purposes. Among the available nanosystems, mesoporous silica nanoparticles (MSNs) stand out due their multifunctionality, biocompatibility and tunable properties make them emerging and actual nanocarriers for specific and controlled drug release. Considering the high demand for diseases prevention and treatment, this review exploits the MSNs fabrication and their behavior in biological media besides highlighting the most of strategies to explore the wide MSNs functionality as engineered, smart and effective controlled drug release nanovehicles for infectious diseases treatment. Graphical Abstract Schematic representation of multifunctional MSNs-based nanoplatforms for infectious diseases treatment.

Indexed as

Drug Delivery SystemsCommunicable DiseasesHumansNanoparticlesPharmacokineticsSilicon DioxideSilicon Dioxidebiological behaviordrug deliveryinfectious diseasesmesoporous silica nanoparticlesmultifunctional nanocarriers

Identifiers

PMID32895867
PMCPMC7476752
OpenAlexW3084354259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.