ArticleJournal of industrial microbiology & biotechnology2020
Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes.
Article in Journal of industrial microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
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Who cites it
22 citing papers in PubMed.
- Application of dielectric spectroscopy combined with simple linear and multivariate modelling for in-line monitoring of biomass concentration in E. coli cultures.Bioprocess and biosystems engineering · 2026Article
- Batch Bayesian auto-tuning for nonlinear Kalman estimators.Scientific reports · 2025Article
- Recent trends in microbial production of alkanes.World journal of microbiology & biotechnology · 2025Review
- Where Biology Meets Engineering: Scaling Up Microbial Nutraceuticals to Bridge Nutrition, Therapeutics, and Global Impact.Microorganisms · 2025Review
- Defining Golden Batches in Biomanufacturing Processes From Internal Metabolic Activity to Detect Process Changes That May Affect Product Quality.Biotechnology and bioengineering · 2025Article
- CGT 4.0: a distant dream or inevitable future? Smart process automation is critical to make efficient scalability of CGT manufacturing a reality.Frontiers in bioengineering and biotechnology · 2025Article
- Real-Time Monitoring in Biomanufacturing with Graphene Field-Effect Transistor Sensors: Detection of pH, Glucose, and Antibodies.GEN biotechnology · 2024Article
- Continuous Biosensor Based on Particle Motion: How Does the Concentration Measurement Precision Depend on Time Scale?ACS sensors · 2024Article
- A Data-Driven Approach for Leveraging Inline and Offline Data to Determine the Causes of Monoclonal Antibody Productivity Reduction in the Commercial-Scale Cell Culture Process.Pharmaceutics · 2024Article
- Single-Use, Metabolite Absorbing, Resonant Transducer (SMART) Culture Vessels for Label-Free, Continuous Cell Culture Progression Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Review
- Automized inline monitoring in perfused mammalian cell culture by MIR spectroscopy without calibration model building.Engineering in life sciences · 2024Article
- How Not to Make the Joint Extended Kalman Filter Fail with Unstructured Mechanistic Models.Sensors (Basel, Switzerland) · 2024Article
- Redox-enabled electronic interrogation and feedback control of hierarchical and networked biological systems.Nature communications · 2023Article
- Bacterial Membrane Vesicles for In Vitro Catalysis.Bioengineering (Basel, Switzerland) · 2023Review
- Application of water-soluble conjugated polymers in intelligent measurement and control of food microbial fermentation process.Frontiers in chemistry · 2023Article
- Continuous process technology for bottom-up synthesis of soluble cello-oligosaccharides by immobilized cells co-expressing three saccharide phosphorylases.Microbial cell factories · 2022Article
- Polymer Encapsulation of Bacterial Biosensors Enables Coculture with Mammalian Cells.ACS synthetic biology · 2022Article
- Editorial: Artificial Intelligence in Environmental Microbiology.Frontiers in microbiology · 2022Article
- Continuous process technology for glucoside production from sucrose using a whole cell-derived solid catalyst of sucrose phosphorylase.Applied microbiology and biotechnology · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The biomanufacturing industry has now the opportunity to upgrade its production processes to be in harmony with the latest industrial revolution. Technology creates capabilities that enable smart manufacturing while still complying with unfolding regulations. However, many biomanufacturing companies, especially in the biopharma sector, still have a long way to go to fully benefit from smart manufacturing as they first need to transition their current operations to an information-driven future. One of the most significant obstacles towards the implementation of smart biomanufacturing is the collection of large sets of relevant data. Therefore, in this work, we both summarize the advances that have been made to date with regards to the monitoring and control of bioprocesses, and highlight some of the key technologies that have the potential to contribute to gathering big data. Empowering the current biomanufacturing industry to transition to Industry 4.0 operations allows for improved productivity through information-driven automation, not only by developing infrastructure, but also by introducing more advanced monitoring and control strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.