Evidence map›Paper›PMID 32895749›Full record

SynthesisHeart failure reviews2021

Takotsubo cardiomyopathy with low ventricular ejection fraction and apical ballooning predicts mortality: a systematic review and meta-analysis.

Lorraine Lok-Wing Chiang, Shek Long Tsang, Jing Xian Lee, Mengqi Gong, Tong Liu, Gary Tse, Dong Chang, Ishan Lakhani, Ka Hou Christien Li

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Heart failure reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Model parameters influencing the cost-effectiveness of sacubitril/valsartan in heart failure: evidence from a systematic literature review.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Lorraine Lok-Wing ChiangLi Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR, China.
Shek Long TsangLi Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR, China.
Jing Xian LeeFaculty of Medicine, Newcastle University, Newcastle, UK.
Mengqi GongTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Gary TseXiamen Cardiovascular Hospital Affiliated to Xiamen University, Xiamen, China.ORCID 0000-0001-5510-1253
Dong ChangXiamen Cardiovascular Hospital Affiliated to Xiamen University, Xiamen, China.
Ishan LakhaniDepartment of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China. ishan.lakhani@outlook.com.
Ka Hou Christien LiFaculty of Medicine, Newcastle University, Newcastle, UK. lijiahao218@gmail.com.
First Affiliated Hospital of Xiamen University · CNNewcastle University · GBSecond Hospital of Tianjin Medical University · CNUniversity of Hong Kong · HKChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo cardiomyopathy (TCM) is characterized by temporary wall motion abnormality of the left ventricle. There is much debate upon the prognostic parameters. We conducted a systematic review and meta-analysis to investigate whether LVEF and the presence of apical ballooning predict long-term mortality in TCM. PubMed and Embase were searched through to October 30, 2017 without language restrictions, followed by an additional search through to February 2, 2020. Our search identified 18 studies that met the inclusion criteria, with a total of 5168 patients. Reduced LVEF as a categorical variable was associated with more than threefold increase in mortality risk in TCM patients (HR 3.10; 95% CI 1.78-5.42; P < 0.0001; I

Indexed as

Takotsubo CardiomyopathyHeart VentriclesHumansPrognosisStroke VolumeApical ballooningEjection fractionMortalityTakotsubo cardiomyopathy

Identifiers

PMID32895749
OpenAlexW3083478803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.