Evidence map›Paper›PMID 32895703›Full record

ArticlePain medicine (Malden, Mass.)2020

Reliability and Validity of the Boston Bedside Quantitative Sensory Testing Battery for Neuropathic Pain.

Alexandra E Koulouris, Robert R Edwards, Kathleen Dorado, Kristin L Schreiber, Asimina Lazaridou, Sharika Rajan, Jeffrey White, Jenniffer Garcia, Christopher Gibbons, Roy Freeman

Open access · bronzeAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

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  17. Precision Medicine in Neuropathic Pain.Handbook of experimental pharmacology · 2023
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  19. Changes in Pain Sensitivity in Treatment for Breast Cancer: A 12-Month Follow-Up Case Series.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alexandra E KoulourisDepartment of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.
Robert R EdwardsDepartment of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.
Kathleen DoradoDepartment of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.
Kristin L SchreiberDepartment of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.
Asimina LazaridouDepartment of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.
Sharika RajanDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Jeffrey WhiteDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Jenniffer GarciaDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Christopher GibbonsDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Roy FreemanDepartment of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Harvard University · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · US

Funding

Opioid-induced change in pain sensitivity and modulation: Links to opioid misuseR21DA041020 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI EDWARDS, ROBERT R · 2016 to 2017
$488k
NIDA NIH HHS R21 DA041020
6 · The paper itself

Abstract

objectiveRecent studies suggest that sensory phenotyping may provide critical information for the diagnosis and management of patients with chronic neuropathic pain (NP). However, many formal quantitative sensory testing (QST) paradigms require expensive equipment, a dedicated location, and substantial time commitments on the part of patient and examiner, highlighting the need for a convenient and portable "bedside" QST battery. We developed and tested a bedside QST battery in a sample of patients with chronic NP.

methodsParticipants (N = 51) attended two in-person visits over approximately two weeks, during which they underwent QST using both laboratory-based equipment and simple, easily accessible bedside tools. Participants also completed questionnaires about their daily pain and NP symptoms.

resultsTest-retest reliability estimates were highly statistically significant and did not differ between bedside (mean r = 0.60) and laboratory-based (mean r = 0.72) QST. Bedside QST variables and corresponding laboratory-based QST variables were highly correlated, suggesting adequate criterion validity for the bedside tests.

conclusionsResults from the present study may have important implications for the sensory phenotyping and subsequent management of patients with chronic NP. Implementation of a protocol that uses inexpensive, portable, and convenient tools may allow for the application of QST in variety of clinical settings and advance NP research.

Indexed as

NeuralgiaPain ThresholdBostonHumansPain MeasurementReproducibility of ResultsNeuropathicPainQuantitative Sensory Testing

Identifiers

PMID32895703
PMCPMC7593797
OpenAlexW3084237929

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.