Evidence map›Paper›PMID 32895611›Full record

ArticleAnnals of medicine and surgery (2012)2020

Acute acalculous cholecystitis on a COVID-19 patient: a case report.

E Mattone, M Sofia, E Schembari, V Palumbo, R Bonaccorso, V Randazzo, G La Greca, C Iacobello, D Russello, S Latteri

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

E MattoneDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
M SofiaDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
E SchembariDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
V PalumboDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
R BonaccorsoDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
V RandazzoDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
G La GrecaDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
C IacobelloInfectious Disease Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
D RusselloDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
S LatteriDepartment of Medical Surgical Sciences and Advanced Technologies "Ingrassia", University of Catania, General Surgery Unit, Cannizzaro Hospital, Via Messina 829, 95126, Catania, Italy.
Ospedale Cannizzaro · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe report an extremely rare case of acute acalculous cholecystitis on a COVID-19 patient. In our knowledge, this is the first report of laparoscopic cholecystectomy performed on a COVID-19 patient. PRESENTATION OF CASE: A COVID-19 patient was diagnosed with acute acalculous cholecystitis and a multidisciplinary team decided to perform a percutaneous transhepatic biliary drainage (PTBD) as the first treatment. SARS-CoV-2 RNA was not found in the bile fluid. Because of deterioration of the patient's clinical conditions, laparoscopic cholecystectomy had to be performed and since the gallbladder was gangrenous, the severe inflammation made surgery difficult to perform. DISCUSSION: Acalculous cholecystitis was related with mechanical ventilation and prolonged total parenteral nutrition, in this case the gangrenous histopathology pattern and the gallbladder wall ischemia was probably caused by vascular insufficiency secondary to severe acute respiratory distress syndrome of COVID-19 pneumonia. The percutaneous transhepatic gallbladder drainage (PTBD) was performed according to Tokyo Guidelines because of high surgical risk. Laparoscopic cholecystectomy was next performed due to no clinical improvement. The absence of viral RNA in the bile highlights that SARS-CoV-2 is not eliminated with the bile while it probably infects small intestinal enterocytes which is responsible of gastrointestinal symptoms such as anorexia, nausea, vomiting, and diarrhoea.

conclusionsAlthough the lack of evidence and guidelines about the management of patient with acute cholecystitis during COVID-19 pandemic, laparoscopic cholecystectomy, at most preceded by PTGBD on high surgical risk patients, remains the gold standard for the treatment of acute cholecystitis on COVID-19 patients.

Indexed as

Acute acalculous cholecystitisCase reportCholecystostomyCOVID-19 pandemicEmergency surgeryLaparoscopy

Identifiers

PMID32895611
PMCPMC7456800
OpenAlexW3082046960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.