Evidence map›Paper›PMID 32895334›Full record

Trial reportGut2021

WASh multicentre randomised controlled trial: water-assisted sigmoidoscopy in English NHS bowel scope screening.

Matthew D Rutter, Rachel Evans, Zoe Hoare, Christian Von Wagner, Jill Deane, Shiran Esmaily, Tony Larkin, Rhiannon Edwards, Seow Tien Yeo, Llinos Haf Spencer and 6 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Water immersion sigmoidoscopy versus standard insufflation for colorectal cancer screening: A cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Matthew D RutterGastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK matt.rutter@nhs.net.ORCID 0000-0001-9507-0295
Rachel EvansNorth Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, UK.
Zoe HoareNorth Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, UK.
Christian Von WagnerBehavioural Science and Health, University College London, London, UK.ORCID 0000-0002-7971-0691
Jill DeaneGastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.
Shiran EsmailyGastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.
Tony LarkinHartlepool, UK.
Rhiannon EdwardsCentre for Health Economics & Medicines Evaluation, Bangor University, Bangor, UK.
Seow Tien YeoCentre for Health Economics & Medicines Evaluation, Bangor University, Bangor, UK.
Llinos Haf SpencerCentre for Health Economics & Medicines Evaluation, Bangor University, Bangor, UK.
Emily HolmesCentre for Health Economics & Medicines Evaluation, Bangor University, Bangor, UK.
Brian P SaundersWolfson Unit for Endoscopy, St Mark's Hospital, London, UK.
Colin J ReesPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Zacharias P TsiamoulosWolfson Unit for Endoscopy, St Mark's Hospital, London, UK.
Iosif BeintarisGastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.
WASh trial team
Bangor University · GBUniversity Hospital of North Tees · GBSt Mark's Hospital · GBNewcastle University · GBUniversity College London · GBUniversity Hospital of Hartlepool · GB

Funding

Department of Health PB-PG-1215-20035
6 · The paper itself

Abstract

objectivesThe English Bowel Cancer Screening Programme invites 55 year olds for a sigmoidoscopy (Bowel Scope Screening (BSS)), aiming to resect premalignant polyps, thus reducing cancer incidence. A national patient survey indicated higher procedural pain than anticipated, potentially impacting on screening compliance and effectiveness. We aimed to assess whether water-assisted sigmoidoscopy (WAS), as opposed to standard CO

designThe WASh (Water-Assisted Sigmoidoscopy) trial was a multicentre, single-blind, randomised control trial for people undergoing BSS. Participants were randomised to either receive WAS or CO

results1123 participants (50% women, mean age 55) were randomised (561 WAS, 562 CO

conclusionIn the context of enema-prepared unsedated screening sigmoidoscopies performed by screening-accredited endoscopists, no difference in patient-reported pain was seen when using either a CO TRIAL REGISTRATION NUMBER: ISRCTN81466870.

Indexed as

WaterColorectal NeoplasmsEarly Detection of CancerEnglandFemaleHumansMaleMiddle AgedPain ManagementPain MeasurementPatient Reported Outcome MeasuresSigmoidoscopySingle-Blind MethodState MedicineWaterclinical trialscolorectal cancer screeningcolorectal neoplasiagastrointesinal endoscopy

Identifiers

PMID32895334
PMCPMC8040154
OpenAlexW3083220743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.