Evidence map›Paper›PMID 32895289›Full record

ArticleDevelopment (Cambridge, England)2020

Loss of

Shannon Romano, Odelya H Kaufman, Florence L Marlow

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Regulation of early gonocyte differentiation in zebrafish.Biochemical Society transactions · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Direct male development in chromosomally ZZ zebrafish.Frontiers in cell and developmental biology · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Sexual determination in zebrafish.Cellular and molecular life sciences : CMLS · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shannon RomanoDepartment of Cell, Developmental and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1020, New York, NY 10029-6574, USA.
Odelya H KaufmanDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Florence L MarlowDepartment of Cell, Developmental and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1020, New York, NY 10029-6574, USA florence.marlow@mssm.edu.ORCID 0000-0002-9362-0342
Albert Einstein College of Medicine · USIcahn School of Medicine at Mount Sinai · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
Oocyte polarity and mRNA localization in ZebrafishR01GM089979 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MARLOW, FLORENCE LOUISE · 2010 to 2018
$3.0M
Molecular genetic basis of sex-specific differentiation of germ cellsR01GM133896 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MARLOW, FLORENCE LOUISE · 2020 to 2023
$1.9M
RNA-binding protein regulation of meiotic progression and sexual differentiationF32HD097898 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ROMANO, SHANNON · 2019 to 2021
$100k
The Role of Rbpms2 in establishing oocyte polarityF30HD082903 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAUFMAN, ODELYA HARTUNG · 2015 to 2016
$97k
NICHD NIH HHS F30 HD082903NICHD NIH HHS F32 HD097898NIGMS NIH HHS R01 GM089979NIGMS NIH HHS R01 GM133896NIGMS NIH HHS T32 GM007288
6 · The paper itself

Abstract

Sex determination and differentiation is a complex process regulated by multiple factors, including factors from the germline or surrounding somatic tissue. In zebrafish, sex-determination involves establishment of a bipotential ovary that undergoes sex-specific differentiation and maintenance to form the functional adult gonad. However, the relationships among these factors are not fully understood. Here, we identify potential Rbpms2 targets and apply genetic epistasis experiments to decipher the genetic hierarchy of regulators of sex-specific differentiation. We provide genetic evidence that the crucial female factor

Indexed as

AnimalsAromataseFemaleGerm CellsMaleOvaryRNA-Binding ProteinsSex Determination ProcessesSex DifferentiationTranscription FactorsZebrafishZebrafish ProteinsAromataseCyp19a1a protein, zebrafishDMRT1 proteinRNA-Binding ProteinsTranscription FactorsZebrafish ProteinsBipotentialCyp19a1aDmrt1RbpmsSex-determinationTGFβ

Identifiers

PMID32895289
PMCPMC7541348
OpenAlexW3083226427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.