Evidence map›Paper›PMID 32895183›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Comparison of B-NDG

Liuliu Guan, Qingqing Zou, Qian Liu, Size Chen

Open access · greenAbstract readComparative Study
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liuliu GuanDepartment of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
Qingqing ZouDepartment of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
Qian LiuGuangdong Provincial Engineering Research Center for Esophageal Cancer Precise Therapy, Guangzhou 510080, China.
Size ChenDepartment of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
First Affiliated Hospital of Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the difference of tumor formation in different mouse strains bearing patient-derived xenograft of esophageal squamous cell carcinoma(ESCC) and establish a better animal model for preclinical study of individualized treatment of ESCC.

methodsThe tumor tissues collected from 22 ESCC patients were used to establish tumor-bearing mouse models in B-NDG

resultsThe tumor-bearing models were established successfully in both NSG mice (50%, 11/22) and BALB/c nude mice (18.18%, 4/22). The average tumor formation time was significantly shorter in NSG mice than in BALB/c nude mice (75.95

conclusionsMouse models bearing xenografts of patient-derived ESCC can be successfully established in both NSG mice and BALB/c nude mice, but the models in the former mouse strain can be more reliable.

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaAnimalsCell Line, TumorCell ProliferationHeterograftsHumansMiceMice, Inbred BALB CMice, NudeXenograft Model Antitumor AssaysBALB/c nude miceesophageal squamous cell carcinomaNSG micepatient-derived xenograft model

Identifiers

PMID32895183
PMCPMC7429172
OpenAlexW3083812388

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.