Evidence map›Paper›PMID 32895169›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Effects of stachyine on apoptosis in an Aβ

Liangchao Qu, Jiajia Huang, Mingda Fan, Yuchen Hao, Jinxiu Yan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liangchao QuDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Jiajia HuangMedical School of Nanchang University, Nanchang 330006, China.
Mingda FanMedical School of Nanchang University, Nanchang 330006, China.
Yuchen HaoMedical School of Nanchang University, Nanchang 330006, China.
Jinxiu YanDepartment of Anesthesia, First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of stachydrine (STA) on apoptosis of Aβ

methodsThe differential genes of STA were analyzed based on GSE85871 data, and the target genes of STA were identified using STITCH database. PC12 cells were treated with Aβ

resultsGSE85871 data showed 37 up-regulated genes and 48 down-regulated genes in cells following treatment with STA. Analysis of the data from the STITCH database indicated that RPS8 and EED were the target genes of STA. Treatment of PC12 cells with Aβ

conclusionsSTA plays an important role in inhibiting the apoptosis of PC12 cells induced by Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisCell SurvivalPC12 CellsPeptide FragmentsRatsAmyloid beta-PeptidesPeptide FragmentsAlzheimer's diseaseapoptosisAβ25-35PC12 cellsstachydrine

Identifiers

PMID32895169
PMCPMC7386225
OpenAlexW3049149930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.