Evidence map›Paper›PMID 32895159›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Periostin inhibits hypoxia-induced oxidative stress and apoptosis in human periodontal ligament fibroblasts

Huili Liu, Yidan Wang, Yangli Yue, Peng Zhang, Yali Sun, Qiaohua Chen

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huili LiuDepartment of Stomatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Yidan WangDepartment of Stomatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Yangli YueSchool of Stomatology, Zhengzhou University, Zhengzhou 450007, China.
Peng ZhangSchool of Stomatology, Zhengzhou University, Zhengzhou 450007, China.
Yali SunDepartment of Stomatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Qiaohua ChenDepartment of Stomatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Zhengzhou Central Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of periostin on hypoxia-induced oxidative stress and apoptosis in human periodontal ligament fibroblasts and the molecular mechanism involved.

methods

resultsHypoxia treatment significantly reduced the cell viability (

conclusionsPeriostin promotes the proliferation, inhibits apoptosis, enhances cellular antioxidant capacity, and reduces inflammatory damage in human periodontal ligament fibroblasts exposed to hypoxia possibly by inhibiting the activation of the p38 MAPK signaling pathway.

Indexed as

ApoptosisPeriodontal LigamentFibroblastsHumansHypoxiaOxidative Stressp38 Mitogen-Activated Protein KinasesSignal Transductionp38 Mitogen-Activated Protein Kinasesapoptosishuman periodontal ligament fibroblastshypoxiaoxidative stressp38 MAPK signaling pathwayperiostin

Identifiers

PMID32895159
PMCPMC7386212
OpenAlexW3083984848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.