Evidence map›Paper›PMID 32895062›Full record

ArticleThe British journal of psychiatry : the journal of mental science2021

Trends in generalised anxiety disorders and symptoms in primary care: UK population-based cohort study.

April Slee, Irwin Nazareth, Nick Freemantle, Laura Horsfall

Abstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. The chronic effects of a combination of herbal extracts (EuphytoseJournal of psychopharmacology (Oxford, England) · 2022
    Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Trends in the registration of anxiety in Belgian primary care from 2000 to 2021: a registry-based study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

April SleeDepartment of Primary Care and Population Health, University College London, UK.ORCID 0000-0003-2469-3916
Irwin NazarethDepartment of Primary Care and Population Health, University College London, UK.
Nick FreemantleComprehensive Clinical Trials Unit, University College London, UK.
Laura HorsfallDepartment of Primary Care and Population Health, University College London, UK.

Funding

Wellcome Trust 209207/Z/17/Z
6 · The paper itself

Abstract

backgroundGeneralised anxiety disorder and symptoms are associated with poor physical, emotional and social functioning and frequent primary and acute care visits. We investigated recent temporal trends in anxiety and related mental illness in UK general practice.

aimsThe aims of this analysis are to examine temporal changes in recording of generalised anxiety in primary care and initial pharmacologic treatments.

methodAnnual incidence rates of generalised anxiety diagnoses and symptoms were calculated from 795 UK general practices contributing to The Health Improvement Network (THIN) database between 1998 and 2018. Poisson mixed regression was used to account for age, gender and general practitioner practice. Subsequent pharmacologic treatment was examined.

resultsGeneralised anxiety recording rates increased in both genders aged 18-24 between 2014 and 2018. For women, the increase was from 17.06 to 23.33/1000 person years at risk (PYAR); for men, 8.59 to 11.65/1000 PYAR. Increases persisted for a composite of anxiety and depression (49.74 to 57.81/1000 PYAR for women; 25.41 to 31.45/1000 PYAR for men). Smaller increases in anxiety were seen in both genders age 25-34 and 35-44. Anxiety rates among older patients remained stable, although a composite of anxiety and depression decreased for older women. About half of drug-naïve patients were prescribed anxiety drugs within 1 year following diagnosis. The most common choice was a selective serotonin reuptake inhibitor. Benzodiazepine prescription rate has fallen steadily.

conclusionsWe observed a substantial increase in general practitioner consulting for generalised anxiety and depression recently, concentrated within younger people and in particular women.

Indexed as

Anxiety DisordersPrimary Health CareAgedCohort StudiesFemaleHumansMaleSelective Serotonin Reuptake InhibitorsUnited KingdomSelective Serotonin Reuptake InhibitorsAnxiety disordersdepressive disordersepidemiologyout-patient treatmentprimary care

Identifiers

PMID32895062
PMCPMC8529638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.