Evidence map›Paper›PMID 32894631›Full record

ArticleHippocampus2020

Developmental onset of enduring long-term potentiation in mouse hippocampus.

Olga I Ostrovskaya, Guan Cao, Cagla Eroglu, Kristen M Harris

Open access · greenAbstract read
In one paragraph

Article in Hippocampus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Teneurins Are SPARCL1 Receptors.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. The how and why for multiple forms of hippocampal LTP.Frontiers in synaptic neuroscience · 2026
    Review
  4. Article
  5. Cage effects on synaptic plasticity and its modulation in a mouse model of fragile X syndrome.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Synaptic Odyssey.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Olga I OstrovskayaDepartment of Neuroscience, Center for Learning and Memory, The University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-8565-6273
Guan CaoDepartment of Neuroscience, Center for Learning and Memory, The University of Texas at Austin, Austin, Texas, USA.
Cagla ErogluDepartment of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA.
Kristen M HarrisDepartment of Neuroscience, Center for Learning and Memory, The University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-1943-4744
The University of Texas at Austin · USDuke University · US

Funding

Synaptic plasticity across the lifespanR01MH095980 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI KRISTEN M HARRIS · 2012 to 2026
$5.0M
Spine and Synaptic Plasticity in Mature HippocampusR37NS021184 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI HARRIS, KRISTEN M · 2005 to 2011
$2.2M
Control of Astrocyte Development and Astrocyte-Synapse InteractionsR01NS102237 · NINDS · DUKE UNIVERSITY · PI EROGLU, CAGLA · 2018 to 2022
$1.9M
Synapse growth and elimination in mature CNSR01MH104319 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI HARRIS, KRISTEN M · 2014 to 2018
$1.8M
Control of synapse formation and maturation by astrocytesR01DA031833 · NIDA · DUKE UNIVERSITY · PI EROGLU, CAGLA · 2012 to 2016
$1.7M
Distance-Dependent Structure and Function of Neuronal DendritesR01NS074644 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI HARRIS, KRISTEN M · 2011 to 2015
$1.7M
ONTOGENY OF STRUCTURE &FUNCTION AT HIPPOCAMPAL SYNAPSESR01NS033574 · NINDS · UNIVERSITY OF TEXAS AUSTIN · PI HARRIS, KRISTEN M · 1996 to 2005
$1.5M
SPINES SYNAPSES AND THE ONTOGENY OF A MEMORY MECHANISMR01NS021184 · NINDS · MEDICAL COLLEGE OF GEORGIA (MCG) · PI HARRIS, KRISTEN M · 1988 to 2003
$1.4M
Synaptic plasticity across the lifespanR56MH095980 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI HARRIS, KRISTEN M · 2019 to 2019
$619k
NIDA NIH HHS R01 DA031833NIH HHS MH-095980NIH HHS MH-104319NIH HHS NS021184NIH HHS NS033574NIH HHS NS074644NIMH NIH HHS R01 MH095980NIMH NIH HHS R01 MH104319NIMH NIH HHS R56 MH095980NINDS NIH HHS R01 NS021184NINDS NIH HHS R01 NS033574NINDS NIH HHS R01 NS074644NINDS NIH HHS R01 NS102237NINDS NIH HHS R37 NS021184
6 · The paper itself

Abstract

Analysis of long-term potentiation (LTP) provides a powerful window into cellular mechanisms of learning and memory. Prior work shows late LTP (L-LTP), lasting >3 hr, occurs abruptly at postnatal day 12 (P12) in the stratum radiatum of rat hippocampal area CA1. The goal here was to determine the developmental profile of synaptic plasticity leading to L-LTP in the mouse hippocampus. Two mouse strains and two mutations known to affect synaptic plasticity were chosen: C57BL/6J and Fmr1

Indexed as

AnimalsAnimals, NewbornExcitatory Postsynaptic PotentialsHippocampusLong-Term PotentiationMaleMiceMice, 129 StrainMice, Inbred C57BLMice, KnockoutMice, TransgenicNeuronal PlasticityOrgan Culture TechniquesSpecies Specificitydevelopmentmaturationsynaptic plasticitytheta-burst potentiation

Identifiers

PMID32894631
PMCPMC8359899
OpenAlexW3083928426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.