SynthesisSurgery today2021
Kono-S anastomosis for Crohn's disease: a systemic review, meta-analysis, and meta-regression.
Synthesis in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Anastomotic configurations and early endoscopic recurrence following ileocolonic resection in Crohn's disease: systematic review and meta-analysis.International journal of colorectal disease · 2026Pooled it
- Safety and effectivity of Kono-S anastomosis in Crohn's patients: a systematic review and Meta-analysis.Langenbeck's archives of surgery · 2024Pooled it
- Surgical features to reduce anastomotic recurrence of Crohn's disease that requires reoperation: a systematic review.Surgery today · 2022Pooled it
- Totally stapled Kono-S anastomosis for Crohn's disease.Techniques in coloproctology · 2022Trial
- Management of Crohn's Disease in Adult Patients: A Contemporary Surgical Perspective.Biomedicines · 2026Review
- [Surgical training on intestinal resections for Crohn's disease : A retrospective analysis of postoperative morbidity].Chirurgie (Heidelberg, Germany) · 2026Article
- Postoperative Recurrence in Crohn's Disease: Pathophysiology, Risk Stratification, and Management Strategies.Journal of clinical medicine · 2025Review
- Kono-S Anastomosis in Pediatric Crohn's Disease: Experience at a Tertiary Referral Center.Journal of clinical medicine · 2025Article
- Obesity-Mediated Inflammation and Its Influence on Inflammatory Bowel Disease: Pathophysiology, Clinical Impact, and Therapeutic Implications.Biomolecules · 2025Review
- First description of endoscopic dilation of stricturing Kono-S anastomosis in Crohn's disease.Techniques in coloproctology · 2025Article
- Anastomosis after Bowel Resection for Crohn's Disease: State of the Art Review.Clinics in colon and rectal surgery · 2025Review
- Role of Mesenteric Defect Closure in Preventing Internal Hernias After Ileocecectomy With Kono-S Anastomosis.Cureus · 2025Article
- New anti-mesenteric delta-shaped stapled anastomosis: Technical report with short-term postoperative outcomes in patients with Crohn's disease.World journal of gastrointestinal surgery · 2024Article
- Impact of different anastomosis methods on post-recurrence after intestinal resection for Crohn's disease: A meta-analysis.World journal of gastrointestinal surgery · 2024Article
- The Reduction of Anastomosis-Related Morbidity Using the Kono-S Anastomosis in Patients with Crohn's Disease: A Meta-Analysis.Journal of clinical medicine · 2024Review
- Management of Post-Operative Crohn's Disease: Knowns and Unknowns.Journal of clinical medicine · 2024Review
- Kono-S anastomosis in Crohn's disease: initial experience in pediatric patients.Pediatric surgery international · 2024Article
- Clinical Update on the Prevention and Management of Postoperative Crohn's Disease Recurrence.Current gastroenterology reports · 2024Review
- Role of visceral fat on postoperative complications and relapse in patients with Crohn's disease after ileocecal resection: Is it overrated?International journal of colorectal disease · 2024Article
- Surgical priorities in abdominal Crohn's disease.Updates in surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Kono-S anastomosis was introduced in 2011 as an alternative anastomosis in Crohn's disease (CD) surgery. Since then, prevailing evidence of the favorable results of the Kono-S anastomosis has been published from around the world. We conducted this study to analyze the effectiveness of the Kono-S anastomosis, by searching Medline, Embase, CNKI, and google scholar. Binominal data were analyzed after Freeman-Tukey double-arcsine transformation. Comparative data were analyzed using the Mantel-Haenszel model for dichotomous outcomes and the mean difference for continuous outcomes. We identified 676 patients who underwent surgery with a Kono-S anastomosis. Surgical recurrence was pooled at an average of 0% (CI: 0.00-0.01) and a reduced mean Rutgeerts score of 1.375 (CI: 0.727-2.023) after Kono-S anastomosis. Endoscopic recurrence after sensitivity analysis was 5% (CI: 0.00-0.15). Complications were rare, with a 3% incidence of ileus (CI: 0.01-0.05), a 4% incidence of small bowel obstruction (CI: 0.01-0.10), a 1% incidence of an anastomotic leak incidence (CI: 0.00-0.03), and a 10% incidence of postoperative infection (CI: 0.03-0.20). Evidence from this meta-analysis favors the Kono-S anastomosis for CD patients, especially for ileocolic anastomosis. Thus, clinicians should consider the applicability of Kono-S anastomosis in respective institutions.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.