ArticleeLife2020
Extensive and diverse patterns of cell death sculpt neural networks in insects.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- From neurons to novelty: Circuit mechanisms shaping courtship evolution.Current opinion in neurobiology · 2025Review
- Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution.Science (New York, N.Y.) · 2025Article
- Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance.Cold Spring Harbor perspectives in biology · 2025Review
- Article
- Evolution of neural circuitry and cognition.Biology letters · 2024Review
- Notch Signaling in Insect Development: A Simple Pathway with Diverse Functions.International journal of molecular sciences · 2023Review
- Input density tunes Kenyon cell sensory responses in the Drosophila mushroom body.Current biology : CB · 2023Article
- Drosophila postembryonic nervous system development: a model for the endocrine control of development.Genetics · 2023Review
- Hacking brain development to test models of sensory coding.bioRxiv : the preprint server for biology · 2023Article
- Evolution of central neural circuits: state of the art and perspectives.Nature reviews. Neuroscience · 2022Review
- Clearing Your Mind: Mechanisms of Debris Clearance After Cell Death During Neural Development.Annual review of neuroscience · 2022Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Changes to the structure and function of neural networks are thought to underlie the evolutionary adaptation of animal behaviours. Among the many developmental phenomena that generate change programmed cell death (PCD) appears to play a key role. We show that cell death occurs continuously throughout insect neurogenesis and happens soon after neurons are born. Mimicking an evolutionary role for increasing cell numbers, we artificially block in the medial neuroblast lineage in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.