Evidence map›Paper›PMID 32894189›Full record

ArticleAntimicrobial resistance and infection control2020

Parental self-medication with antibiotics for children promotes antibiotic over-prescribing in clinical settings in China.

Jiayao Xu, Xiaomin Wang, Kai Sing Sun, Leesa Lin, Xudong Zhou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Jiayao XuInstitute of Social Medicine, School of Medicine, Zhejiang University, Hangzhou, China.
Xiaomin WangInstitute of Social Medicine, School of Medicine, Zhejiang University, Hangzhou, China.
Kai Sing SunDepartment of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong, China.
Leesa LinDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Xudong ZhouInstitute of Social Medicine, School of Medicine, Zhejiang University, Hangzhou, China. zhouxudong@zju.edu.cn.ORCID 0000-0002-0784-5343
Zhejiang University · CNLondon School of Hygiene & Tropical Medicine · GBUniversity of Hong Kong · HKZhejiang University-University of Edinburgh Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-medication with antibiotics (SMA) is one of the most dangerous inappropriate antibiotic use behaviors. This study aims to investigate the impact of parental SMA for children before a consultation on their doctor's subsequent antibiotic prescribing behavior, including intravenous (IV) antibiotic use in the clinical setting of China.

methodsA cross-sectional survey was conducted between June 2017 and April 2018 in three provinces of China. A total of 9526 parents with children aged 0-13 years were investigated. Data from 1275 parents who had self-medicated their children and then visited a doctor in the past month were extracted and analyzed.

resultsOne-third (410) of the studied children had parental SMA before the consultation and 83.9% of them were subsequently prescribed antibiotics by doctors. Children with parental SMA were more likely to be prescribed antibiotics (aOR = 7.79, 95% CI [5.74-10.58]), including IV antibiotics (aOR = 3.05, 95% CI [2.27-4.11]), and both oral and IV antibiotics (aOR = 3.42, 95% CI [2.42-4.84]), than children without parental SMA. Parents with SMA behaviors were more likely to request antibiotics (aOR = 4.05, 95% CI [2.59-6.31]) including IV antibiotics (aOR = 2.58, 95% CI [1.40-4.76]), and be fulfilled by doctors (aOR = 3.22, 95% CI [1.20-8.63]).

conclusionsTailored health education for parents is required in both community and clinical settings to discourage parental SMA for children. The doctors should not prescribe unnecessary antibiotics to reinforce parents' SMA behaviors. We recommend expanding the current IV antibiotics ban in outpatient settings of China to cover outpatient pediatrics.

Indexed as

Administration, IntravenousAdministration, OralAdolescentChildChild, PreschoolChinaClinical Decision-MakingCross-Sectional StudiesFemaleHealth EducationHumansInappropriate PrescribingInfantInfant, NewbornMaleParentsAntibiotic prescriptionAntibiotic useChildrenClinicalMedical decision making

Identifiers

PMID32894189
PMCPMC7487542
OpenAlexW3083070739

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.