Evidence map›Paper›PMID 32894182›Full record

ArticleAntimicrobial resistance and infection control2020

Point prevalence survey of antimicrobial use in three hospitals in North-Eastern Tanzania.

Pius G Horumpende, Stephen E Mshana, Elise F Mouw, Blandina T Mmbaga, Jaffu O Chilongola, Quirijn de Mast

Abstract readMulticenter Study
In one paragraph

Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pius G HorumpendeKilimanjaro Christian Medical University College, P.O. BOX 2240, Moshi, Tanzania. p.horumpende@kcri.ac.tz.ORCID 0000-0003-1241-6997
Stephen E MshanaCatholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania.
Elise F MouwDepartment of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Blandina T MmbagaKilimanjaro Christian Medical University College, P.O. BOX 2240, Moshi, Tanzania.
Jaffu O ChilongolaKilimanjaro Christian Medical University College, P.O. BOX 2240, Moshi, Tanzania.
Quirijn de MastDepartment of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania.

methodsA PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 h and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day.

resultsA total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. Ceftriaxone (n = 94, 29.8%), metronidazole (n = 79, 23.9%) and other antibiotics belonging to the penicillin class (n = 89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases.

conclusionOur study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.

Indexed as

AdultAntibiotic ProphylaxisCeftriaxoneDrug Resistance, MicrobialDrug UtilizationFemaleHumansMaleMetronidazolePenicillinsPovertyPrevalenceTanzaniaTertiary Care CentersCeftriaxoneMetronidazolePenicillinsAntibiotic prescriptionAntibiotic stewardshipAntimicrobial resistancePoint prevalence surveyTanzania

Identifiers

PMID32894182
PMCPMC7487761

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.