Evidence map›Paper›PMID 32894172›Full record

ArticleParasites & vectors2020

Molecular epidemiology of a fatal sarcoptic mange epidemic in endangered San Joaquin kit foxes (Vulpes macrotis mutica).

Jaime L Rudd, Deana L Clifford, Brian L Cypher, Joshua M Hull, A Jane Riner, Janet E Foley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  14. First description of sarcoptic mange in an Iberian hare (Current research in parasitology & vector-borne diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jaime L RuddDepartment of Medicine and Epidemiology, University of California, Davis, CA, 95616, USA. Jaime.Rudd@wildlife.ca.gov.
Deana L CliffordDepartment of Medicine and Epidemiology, University of California, Davis, CA, 95616, USA.
Brian L CypherEndangered Species Recovery Program, California State University, Stanislaus, Turlock, CA, 95382, USA.
Joshua M HullUnited States Fish and Wildlife Service, Sacramento, CA, 95825, USA.
A Jane RinerDepartment of Medicine and Epidemiology, University of California, Davis, CA, 95616, USA.
Janet E FoleyDepartment of Medicine and Epidemiology, University of California, Davis, CA, 95616, USA.
University of California, Davis · USCalifornia Department of Fish and Wildlife · USCalifornia State University, Stanislaus · USUnited States Fish and Wildlife Service · US

Funding

Morris Animal Foundation D15ZO-013U.S. Fish and Wildlife Service F16AP00008
6 · The paper itself

Abstract

backgroundIn 2013, sarcoptic mange, caused by Sarcoptes scabiei mites, precipitated a catastrophic decline of the formerly stable urban population of endangered San Joaquin kit foxes (Vulpes macrotis mutica) in Bakersfield, California, USA. In 2019, a smaller sarcoptic mange outbreak affected kit foxes 58 km southwest of Bakersfield in the town of Taft, California. To determine whether the Taft outbreak could have occurred as spillover from the Bakersfield outbreak and whether epidemic control efforts must involve not only kit foxes but also sympatric dogs (Canis lupus familiaris), coyotes (Canis latrans), and red foxes (Vulpes vulpes), we evaluated genotypes and gene flow among mites collected from each host species.

methodsWe used 10 Sarcoptes microsatellite markers (SARM) to perform molecular typing of 445 S. scabiei mites collected from skin scrapings from twenty-two infested kit foxes, two dogs, five coyotes, and five red foxes from Bakersfield, Taft, and other nearby cities.

resultsWe identified 60 alleles across all SARM loci; kit fox- and red fox-derived mites were relatively monomorphic, while genetic variability was greatest in Bakersfield coyote- and dog-derived mites. AMOVA analysis documented distinct mite populations unique to hosts, with an overall F

conclusionsThese results confirm the close relationship between the Taft and Bakersfield outbreaks. Although a spillover event likely initiated the kit fox mange outbreak, mite transmission is now primarily kit fox-to-kit fox. Therefore, any large-scale population level intervention should focus on treating kit foxes within the city.

Indexed as

AnimalsAnimals, WildCaliforniaCitiesCoyotesDogsEndangered SpeciesFoxesGene FlowGenotypeGenotyping TechniquesMicrosatellite RepeatsMite InfestationsMolecular EpidemiologySarcoptes scabieiScabiesBakersfieldCaliforniaHost specificityManagementMicrosatellitesMitesSarcoptes scabieiWildlife

Identifiers

PMID32894172
PMCPMC7487715
OpenAlexW3084144749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.