Evidence map›Paper›PMID 32894102›Full record

ArticleBMC infectious diseases2020

HIV-1 infection among women in Israel, 2010-2018.

Tali Wagner, Karen Olshtain-Pops, Marina Wax, Olivia Horwitz, Rachel Shirazi, Yael Gozlan, Hadar Volnowitz, Ella Mendelson, Itzchak Levy, Orna Mor

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Determinants of Direct Costs of HIV-1 Outpatient Care in Israel.International journal of environmental research and public health · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tali WagnerSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv-Yafo, Israel.
Karen Olshtain-PopsHadassah Medical Center, Jerusalem, Israel.
Marina WaxNational HIV and Viral Hepatitis Reference Laboratory, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel.
Olivia HorwitzNational HIV and Viral Hepatitis Reference Laboratory, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel.
Rachel ShiraziNational HIV and Viral Hepatitis Reference Laboratory, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel.
Yael GozlanNational HIV and Viral Hepatitis Reference Laboratory, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel.
Hadar VolnowitzNational HIV and Viral Hepatitis Reference Laboratory, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel.
Ella MendelsonSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv-Yafo, Israel.
Itzchak LevySackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv-Yafo, Israel.
Orna MorSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv-Yafo, Israel. orna.mor@sheba.health.gov.il.ORCID http://orcid.org/0000-0003-3207-4226
Sheba Medical Center · ILTel Aviv University · ILHadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough women comprise 33% of the HIV-1-carriers in Israel, they have not previously been considered a risk group requiring special attention. Immigration waves from countries in Africa and in East Europe may have changed the local landscape of women diagnosed with HIV-1. Here, we aimed to assess viral and demographic characteristics of HIV-1-positive women identified in Israel between 2010 and 2018.

methodsAll > 16 year-old, HIV-1-infected women, diagnosed in Israel in 2010-2018, (n = 763) registered in the National HIV reference laboratory were included in this cross-sectional study. Demographic and clinical characteristics were extracted from the database. Viral subtypes and transmitted drug resistance mutations (TDRM) were determined in 337 (44.2%) randomly selected samples collected from treatment-naive women.

resultsMedian age at diagnosis was 38 years. Most (73.3%) women were immigrants from the former Soviet Union (FSU) (41.2%, 314) or sub-Saharan Africa (SSA) (32.2%, 246) and carried subtype A (79.7%) or C (90.3%), respectively. Only 11.4% (87) were Israeli-born women. Over the years, the prevalence of women from SSA decreased while that of women from FSU increased significantly (p < 0.001). The median CD4

conclusionsMost HIV-1-positive women diagnosed in Israel in 2010-2018 were immigrants, with the relative ratio of FSU immigrants increasing in recent years. The high proportion of women diagnosed with resistance mutations, particularly, the yearly increase in the frequency of NNRTI mutations, support the national policy of resistance testing at baseline.

Indexed as

AdultAntiviral AgentsCD4 Lymphocyte CountCohort StudiesCross-Sectional StudiesDrug Resistance, ViralEmigrants and ImmigrantsFemaleHIV-1HIV InfectionsHumansIsraelMiddle AgedMutationPrevalenceReverse Transcriptase InhibitorsAntiviral AgentsReverse Transcriptase InhibitorsHIV-1Resistance-testingTransmitted drug resistance mutations (TDRM)Women

Identifiers

PMID32894102
PMCPMC7487961
OpenAlexW3083605254

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.