Evidence map›Paper›PMID 32893974›Full record

ReviewJournal of cachexia, sarcopenia and muscle2020

Muscular weakness and muscle wasting in the critically ill.

Joerg C Schefold, Tobias Wollersheim, Julius J Grunow, Markus M Luedi, Werner J Z'Graggen, Steffen Weber-Carstens

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of cachexia, sarcopenia and muscle, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 98 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 7 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07017517 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Physical Therapy on NLRP3 Inflammasome Activation and Muscle Atrophy in Critical Illness Myopathy (PT-NLRP3-CIM).

TypeinterventionalSponsorUniversity of ChileRan2026 to 2027Enrolled24ConditionsCritical Illness MyopathyArmsMotomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
NCT07032870 recruitingnot on this mapstarted 2025, after this paper: background citation

Pilot Study: Validation of Operators and Inter-Evaluator Variability in Diagnostic Strategies for ICU-Acquired Weakness (NMusICU-R)

TypeobservationalSponsorUniversity of ChileRan2025 to 2025Enrolled37ConditionsCritical Illness
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 7 syntheses or guidelines pooled it, 173 citations in OpenAlex.

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  5. Sarcopenia and Mortality Risk of Patients with Sepsis: A Meta-Analysis.International journal of clinical practice · 2022
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  7. Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review.Journal of applied physiology (Bethesda, Md. : 1985) · 2021
    Pooled it
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Joerg C SchefoldDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-9162-5724
Tobias WollersheimDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Julius J GrunowDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Markus M LuediDepartment of Anaesthesiology and Pain Medicine, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.
Werner J Z'GraggenDepartment of Neurology and Neurosurgery, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.
Steffen Weber-CarstensDepartment of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Humboldt-Universität zu Berlin · DEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Muscular DiseasesPolyneuropathiesCritical IllnessFemaleHumansIntensive Care UnitsMaleMusclesMuscle WeaknessCritical illness myopathyCritical illness polyneuropathyDysphagiaICU-acquired weaknessSepsisSwallowing disorder

Identifiers

PMID32893974
PMCPMC7749542
OpenAlexW3084022240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.