ArticleJournal of veterinary internal medicine2020
Protease inhibitors, inflammatory markers, and their association with outcome in dogs with naturally occurring acute pancreatitis.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 23 citations in OpenAlex.
- PasteurizedMicrobiology spectrum · 2026Article
- Diffuse alveolar damage, acute respiratory distress syndrome (ARDS), and non-cardiogenic pulmonary edema. Part 1: ARDS endotypes, including systemic inflammatory response syndrome and sepsis, with dog and cat examples.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2026Review
- Clinical Utility of Adapted Modified Canine Activity Index (aMCAI) in Canine Acute Pancreatitis: A Prospective Observational Study.Animals : an open access journal from MDPI · 2026Article
- The comparison of acute phase proteins in experimentally induced canine acute pancreatitis.BMC veterinary research · 2026Article
- Dogs with advanced myxomatous mitral valve disease have evidence of gastrointestinal bacterial translocation and systemic inflammation.PloS one · 2025Article
- Dogs with sepsis are more hypercoagulable and have higher fibrinolysis inhibitor activities than dogs with non-septic systemic inflammation.Frontiers in veterinary science · 2025Article
- Allogenic Adipose-Derived Mesenchymal Stem Cell Infusion for the Management of Acute-Onset Pancreatitis in Dogs: A Pilot Study.Animals : an open access journal from MDPI · 2024Article
- Serum αVeterinary sciences · 2023Article
- Red Blood Cell Distribution Width as a Novel Parameter in Canine Disorders: Literature Review and Future Prospective.Animals : an open access journal from MDPI · 2023Review
- Utility of 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin)-ester-lipase for monitoring dogs with chronic pancreatitis.Journal of veterinary internal medicine · 2023Article
- Impact of fatty acid composition on markers of exocrine pancreatic stimulation in dogs.PloS one · 2023Article
- The prognostic value of procalcitonin in critically ill cases of systematic inflammatory response syndrome in dogs.Comparative clinical pathology · 2023Article
- Progression of lipase activity and pancreatic lipase immunoreactivity in dogs hospitalized for acute pancreatitis and correlation with clinical features.Journal of veterinary internal medicine · 2023Article
- Prognostic Role of Red Cell Distribution Width and Other Routine Clinico-Pathological Parameters in Dogs with Acute Pancreatitis.Animals : an open access journal from MDPI · 2022Article
- Effects of medical history and clinical factors on serum lipase activity and ultrasonographic evidence of pancreatitis: Analysis of 234 dogs.Journal of veterinary internal medicine · 2022Article
- Prevalence of ultrasonographic gastrointestinal wall changes in dogs with acute pancreatitis: A retrospective study (2012-2020).Journal of veterinary internal medicine · 2022Article
- New insights into the etiology, risk factors, and pathogenesis of pancreatitis in dogs: Potential impacts on clinical practice.Journal of veterinary internal medicine · 2022Review
- Changes in Acute-Phase Proteins in Plasma during the Periparturient Period of Dairy Goats.Veterinary sciences · 2021Article
- Advances in the diagnosis of acute pancreatitis in dogs.Journal of veterinary internal medicine · 2021Review
- Corticosteroid treatment for acute/acute-on-chronic experimental and naturally occurring pancreatitis in several species: a scoping review to inform possible use in dogs.Acta veterinaria Scandinavica · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAcute pancreatitis (AP) presumably is associated with pancreatic protease activation, protease inhibitor (PI) depletion, and inflammatory mediator secretion.
objectivesExamine PIs and inflammatory mediator concentrations in dogs with AP and their association with death. ANIMALS: Thirty-one dogs diagnosed with AP based on clinical signs, ultrasonographic findings, and increased canine pancreatic lipase immunoreactivity (cPLI) and 51 healthy control dogs.
methodsAntithrombin and α
resultsMortality rate was 19%. Antithrombin activity was lower (P = .004) and maximal CRP, IL-6, and TNF-α concentrations higher (P < .04) in the AP group compared to the controls, whereas IL-2, IL-8, α CONCLUSIONS AND CLINICAL IMPORTANCE: Systemic inflammation in dogs with AP is manifested by increased inflammatory mediator concentrations, correlating with cPLI and CRP concentrations. Hypoantithrombinemia is associated with death. Serum concentrations of α
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.