Evidence map›Paper›PMID 32893708›Full record

ArticleJournal of the American Heart Association2020

Association of Autoimmune Vasculitis and Incident Atrial Fibrillation: A Population-Based Case-Control Study.

Rowlens M Melduni, Leslie T Cooper, Bernard J Gersh, Kenneth J Warrington, Kent R Bailey, Marian T McEvoy, Hirohito Kita, Hon-Chi Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. COVID-19 HEART unveiling as atrial fibrillation: pathophysiology, management and future directions for research.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rowlens M MelduniDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Leslie T CooperDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Bernard J GershDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Kenneth J WarringtonDivision of Rheumatology Mayo Clinic Rochester Minnesota USA.
Kent R BaileyDivision of Biomedical Statistics and Informatics Mayo Clinic Rochester Minnesota USA.
Marian T McEvoy
Hirohito KitaDivisions of Allergy and Immunology Mayo Clinic Rochester Minnesota USA.
Hon-Chi LeeDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Mayo Clinic · USMarian University - Indiana · US

Funding

The Role of Autoimmune Mechanisms in the Pathogenesis of Atrial FibrillationK01HL135288 · NHLBI · MAYO CLINIC ROCHESTER · PI MELDUNI, ROWLENS MICHEL · 2017 to 2021
$854k
NHLBI NIH HHS K01 HL135288
6 · The paper itself

Abstract

Background Recent investigations suggest that inflammation and autoimmunity might have a role in the pathophysiology of atrial fibrillation (AF). Given that abnormal ventriculovascular coupling often coexists with AF, we hypothesize that autoimmune vasculitis plays a significant role in the pathogenetic mechanism of AF. Methods and Results A standardized retrospective population-based case-control study was conducted to evaluate the association between autoimmune vasculitis and AF, and all-cause mortality. The study included 8459 patients with a new diagnosis of AF and 8459 age-, sex-, and registration calendar year-matched controls in Olmsted County, Minnesota, between January 1, 1980 and December 31, 2010. The association of each clinical characteristic, diagnosis, and treatment was assessed using conditional logistic regression to account for the matched case-control study design. Cox proportional hazards regression models and Kaplan-Meier curves were used to detect independent predictors of mortality and examine cumulative survival. Of a total of 16 918 patients (mean age 72.3+14.4 years; 48.7% women), 320 (1.9%) were diagnosed with autoimmune vasculitis before the index date during the 30-year period. Among the cases, the prevalence of any autoimmune vasculitis was 2.3%, whereas the frequency of autoimmune vasculitis in controls was 1.5% (

Indexed as

AgedAtrial FibrillationAutoimmune DiseasesCase-Control StudiesHumansIncidenceKaplan-Meier EstimateLogistic ModelsMaleMinnesotaProportional Hazards ModelsRetrospective StudiesVasculitisarrhythmiaatrial fibrillationoutcomesurvivalvasculitis

Identifiers

PMID32893708
PMCPMC7727002
OpenAlexW3083552136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.