Evidence map›Paper›PMID 32893517›Full record

ArticleJournal of Korean medical science2020

Impact of Molecular Drug Susceptibility Testing on the Time to Multidrug-resistant Tuberculosis Treatment Initiation.

Doosoo Jeon, Hyungseok Kang, Yong Soo Kwon, Jae Joon Yim, Tae Sun Shim

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Doosoo JeonDepartment of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0002-8206-9487
Hyungseok KangDepartment of Chest Medicine, Masan National Tuberculosis Hospital, Masan, Korea.ORCID https://orcid.org/0000-0002-9175-0012
Yong Soo KwonDepartment of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0001-5121-4488
Jae Joon YimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9605-0074
Tae Sun ShimDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. shimts@amc.seoul.kr.ORCID https://orcid.org/0000-0001-6653-816X

Funding

Korea Centers for Disease Control and Prevention 2019-E3101-00
6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate the current status and trends in the coverage of molecular drug susceptibility testing (mDST), and the impact of mDST on the time to multidrug-resistant tuberculosis (MDR-TB) treatment initiation in Korea.

methodsWe included confirmed rifampin-resistant (RR)/MDR-TB patients who submitted application forms for novel drug uses to the National TB Expert Review Committee from September 1, 2016 to November 30, 2019. We retrospectively reviewed their medical records.

resultsOf the 621 MDR/RR-TB patients, mDST was performed in 442 (71.2%); Xpert MTB/RIF (Xpert) alone in 109 (17.6%), MTBDR

conclusionmDST coverage is gradually increasing and contributes to reducing the time to MDR-TB treatment initiation. Further efforts are needed to achieve universal access to mDST and to properly integrate mDST into routine clinical practice.

Indexed as

AdultAgedAntitubercular AgentsDatabases, FactualFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisProportional Hazards ModelsRetrospective StudiesRifampinTime-to-TreatmentTuberculosis, Multidrug-ResistantAntitubercular AgentsRifampinDrug ResistanceKoreaMultidrug-Resistant TuberculosisTime to TreatmentTuberculosis

Identifiers

PMID32893517
PMCPMC7476798

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.