Evidence map›Paper›PMID 32893497›Full record

ArticleBrain and behavior2020

Preliminary results of posterior contralateral cervical 7 nerve transposition in the treatment of upper limb plegia after a stroke.

Jingyu Guan, Jun Lin, Xueqing Guan, Qiang Jin, Lei Chen, Qiao Shan, Jianheng Wu, Xiaodong Cai, Doudou Zhang, Wei Tao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Jingyu GuanDepartments of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0000-0002-7606-8103
Jun LinDepartments of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Xueqing GuanCollege of Medicine, China Medical University, Shenyang, China.
Qiang JinDepartments of Anesthesiology, General Hospital of Northern Theater Command, Shenyang, China.
Lei ChenDepartments of Neurosurgery, Tianjin Fifth Central Hospital, Tianjin, China.
Qiao ShanDepartment of Neurosurgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jianheng WuDepartment of Neurosurgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaodong CaiDepartment of Functional Neuro, Shenzhen Second People's Hospital, the First Hospital of Shenzhen University, Shenzhen, China.
Doudou ZhangDepartment of Functional Neuro, Shenzhen Second People's Hospital, the First Hospital of Shenzhen University, Shenzhen, China.
Wei TaoShenzhen University General Hospital, Shenzhen, China.
Fuyong ChenShenzhen University General Hospital, Shenzhen, China.
Yili ChenDepartment of Neurosurgery, Fourth Affiliated Hospital of Medical College of Zhejiang University, Yiwu, China.
Shaofeng YangDepartment of Neurosurgery, Renji Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.
Youwu FanDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Heming WuDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Han ZhangDepartment of Neurosurgery, Chengdu Southwest Brain Hospital, Chengdu, China.
General Hospital of Shenyang Military Region · CNFifth Affiliated Hospital of Zhengzhou University · CNNanjing Medical University · CNShenzhen Second People's Hospital · CNShenzhen University · CNChina Medical University · CNFifth Tianjin Central Hospital · CNFourth Affiliated Hospital of China Medical University · CNRenji Hospital · CNSouthwest Petroleum University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to explore a shorter and safer contralateral C7 transposition pathway for the treatment of central upper limb paralysis.

methodsFrom July 2018 to March 2019, 10 patients with central upper limb paralysis underwent posterior cervical 7 nerve transposition. The age of these patients ranged within 31-58 years old (average: 44 years old). These patients comprised of eight male patients and two female patients. Nine patients had cerebral hemorrhage, and one patient had a cerebral infarction. Furthermore, nine patients presented with spastic paralysis of the upper limbs and one patient presented with nonspastic paralysis. The duration of plegia before the operation ranged from 6 to 60 months (average: 26 months). The surgical procedure included transposition of the contralateral cervical 7 nerve root via a posterior vertebral approach under general anesthesia, and the distal part of the contralateral cervical 7 nerve was anastomosed with the proximal part of the ipsilateral cervical 7 nerve.

resultsThe length of the contralateral cervical 7 nerve was 5.16 ± 0.21 cm, which was directly anastomosed with the ipsilateral cervical 7 nerve. Neither case needed nerve transplantation. Most patients had temporary numbness in their healthy fingers, which all disappeared within three months. Up to now, the follow-up results are as follows: The spasticity of the affected upper limbs in five patients is lower than that before the operation, the pain and temperature sensation of the affected upper limbs in six patients are better than before the operation.

conclusionThe distance of nerve transposition can be shortened by a posterior vertebral approach operation, where the contralateral C7 nerve can be anastomosed directly with the ipsilateral C7 nerve which may be effective for nerve regeneration and functional recovery. However, this conclusion still needs further research and verification.

Indexed as

Nerve TransferStrokeAdultCervical VertebraeFemaleHumansMaleMiddle AgedParalysisUpper Extremitycentral paralysiscontralateral C7 nerve rootnerve root transferposterior spinal route

Identifiers

PMID32893497
PMCPMC7667331
OpenAlexW3084047429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.