Evidence map›Paper›PMID 32893386›Full record

ArticleNMR in biomedicine2021

The feasibility of quantitative MRI of extra-ocular muscles in myasthenia gravis and Graves' orbitopathy.

Kevin R Keene, Luc van Vught, Nienke M van de Velde, Isabeau A Ciggaar, Irene C Notting, Stijn W Genders, Jan J G M Verschuuren, Martijn R Tannemaat, Hermien E Kan, Jan-Willem M Beenakker

Open access · hybridAbstract read
In one paragraph

Article in NMR in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  7. Application of quantitative orbital analysis to assess the activity of Graves' ophthalmopathy.American journal of nuclear medicine and molecular imaging · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kevin R KeeneCJ Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0001-9300-9888
Luc van VughtCJ Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0001-8290-9071
Nienke M van de VeldeDepartment of Neurology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-1541-130X
Isabeau A CiggaarCJ Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Irene C NottingDepartment of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-3625-0752
Stijn W GendersDepartment of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-4777-560X
Jan J G M VerschuurenDepartment of Neurology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-4572-1501
Martijn R TannemaatDepartment of Neurology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-2929-0390
Hermien E KanCJ Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0002-5772-7177
Jan-Willem M BeenakkerCJ Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-0479-5587
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although quantitative MRI can be instrumental in the diagnosis and assessment of disease progression in orbital diseases involving the extra-ocular muscles (EOM), acquisition can be challenging as EOM are small and prone to eye-motion artefacts. We explored the feasibility of assessing fat fractions (FF), muscle volumes and water T2 (T2

Indexed as

Magnetic Resonance ImagingAdiposityAdultAutomationFeasibility StudiesFemaleGraves OphthalmopathyHumansImage Processing, Computer-AssistedMaleMiddle AgedMuscle, SkeletalMyasthenia GravisOrgan SizeReproducibility of ResultsWaterWaterextra-ocular muscleseye diseaseseye musclesGraves' orbitopathymuscle MRImyasthenia gravisquantitative MRI

Identifiers

PMID32893386
PMCPMC7757175
OpenAlexW3083913282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.