Evidence map›Paper›PMID 32893382›Full record

ReviewBritish journal of clinical pharmacology2022

European research networks to facilitate drug research in children.

Mark A Turner, Katharine Cheng, Saskia de Wildt, Heidrun Hildebrand, Sabah Attar, Paolo Rossi, Donato Bonifazi, Adriana Ceci, Joana Claverol, Begonya Nafria and 1 more

Abstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Access to novel drugs and therapeutics for children and youth: Eliciting citizens' values to inform public funding decisions.Health expectations : an international journal of public participation in health care and health policy · 2023
    Article
  6. Article
  7. Review
  8. European research networks to facilitate drug research in children.British journal of clinical pharmacology · 2022
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mark A TurnerInstitute of Lifecourse and Medical Sciences, University of Liverpool, Liverpool Health Partners, Liverpool, UK.ORCID 0000-0002-5299-8656
Katharine ChengChild Health Innovation Leadership Department (CHILD), Johnson and Johnson, High Wycombe, UK.
Saskia de WildtRadboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Heidrun HildebrandPediatric Development, Research & Development, Pharmaceuticals, Bayer AG, Berlin, Germany.
Sabah AttarInstitute of Lifecourse and Medical Sciences, University of Liverpool, Liverpool Health Partners, Liverpool, UK.
Paolo RossiAcademic Department of Pediatrics (DPUO), Unit of Perinatal infection and congenital infectious diseases, Bambino Gesu Children's Hospital-University of Rome Tor Vergata, Rome, Italy.
Donato BonifaziConsorzio per Valutazioni Biologiche e Farmacologiche, Bari, Italy.
Adriana CeciFondazione per la Ricerca Farmacologica Gianni Benzi Onlus, Bari, Italy.
Joana ClaverolInstitut de Recerca Sant Joan de Deu, Sant Joan de Deu Research Foundation, Barcelona, Spain.
Begonya NafriaInstitut de Recerca Sant Joan de Deu, Sant Joan de Deu Research Foundation, Barcelona, Spain.
Carlo GiaquintoDivision of Pediatric Infectious Diseases, Department of Woman's and Child's Health, University of Padua, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paediatric drug development faces several barriers. These include fragmentation of stakeholders and inconsistent processes during the conduct of research. This review summarises recent efforts to overcome these barriers in Europe. Two exemplar initiatives are described. The European Paediatric Translational Research Infrastructure facilitates preclinical research and other work that underpins clinical trials. conect4children facilitates the design and implementation of clinical trials. Both these initiatives listen to the voices of children and their advocates. Coordination of research needs specific effort that supplements work on science, resources and the policy context.

Indexed as

Pharmaceutical ResearchChildEuropeHumansTranslational Research, Biomedicaldrug developmentpaediatricresearch infrastructure

Identifiers

PMID32893382
PMCPMC9546307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.