Evidence map›Paper›PMID 32892777›Full record

ArticleCambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees2020

Pediatric Deep Brain Stimulation for Dystonia: Current State and Ethical Considerations.

Katrina A MuÑoz, Jennifer Blumenthal-Barby, Eric A Storch, Laura Torgerson, Gabriel LÁzaro-MuÑoz

Open access · greenAbstract read
In one paragraph

Article in Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katrina A MuÑoz
Jennifer Blumenthal-Barby
Eric A Storch
Laura Torgerson
Gabriel LÁzaro-MuÑoz

Funding

Pediatric Deep Brain Stimulation: Neuroethics and Decision Making: Training SupplementRF1MH121371 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI BLUMENTHAL-BARBY, JENNIFER, LAZARO-MUNOZ, GABRIEL · 2019 to 2020
$1.9M
NIMH NIH HHS RF1 MH121371
6 · The paper itself

Abstract

Dystonia is a movement disorder that can have a debilitating impact on motor functions and quality of life. There are 250,000 cases in the United States, most with childhood onset. Due to the limited effectiveness and side effects of available treatments, pediatric deep brain stimulation (pDBS) has emerged as an intervention for refractory dystonia. However, there is limited clinical and neuroethics research in this area of clinical practice. This paper examines whether it is ethically justified to offer pDBS to children with refractory dystonia. Given the favorable risk-benefit profile, it is concluded that offering pDBS is ethically justified for certain etiologies of dystonia, but it is less clear for others. In addition, various ethical and policy concerns are discussed, which need to be addressed to optimize the practice of offering pDBS for dystonia. Strategies are proposed to help address these concerns as pDBS continues to expand.

Indexed as

Deep Brain StimulationDystoniaChildGlobus PallidusHumansQuality of LifeTreatment Outcomedeep brain stimulationdystonianeuroethicspediatric

Identifiers

PMID32892777
PMCPMC9426302
OpenAlexW3084401557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.