ArticleCambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees2020
The Impact of Incidental Findings Detected During Brain Imaging on Research Participants of the Rotterdam Study: An Interview Study.
Article in Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Choosing wisely in neuroradiology: evaluating CT and MR utilization trends in Europe.European radiology · 2026Pooled it
- Bilateral distal femoral sclerotic lesions in elderly women: a distinct benign imaging pattern associated with fat necrosis and dystrophic calcification.European radiology · 2026Article
- Article
- Evaluating musculoskeletal imaging communication interventions using behavioural science: a scoping review using the COM-B model.BMJ open · 2025Article
- Prevalence and Clinical Impact of Incidental Findings on Preoperative Computed Tomography for Hip Arthroscopy.Orthopaedic journal of sports medicine · 2025Article
- Exploring health and disease concepts in healthcare practice: an empirical philosophy of medicine study.BMC medical ethics · 2024Article
- Cardiovascular Disease and Alzheimer's Disease: The Heart-Brain Axis.Journal of the American Heart Association · 2023Review
- The meaning of screening: detection of brain metastasis in the adjuvant setting for stage III melanoma.ESMO open · 2022Article
- Impact of incidental findings on young adult participants in brain imaging research: an interview study.European radiology · 2022Article
- The impact of reporting magnetic resonance imaging incidental findings in the Canadian alliance for healthy hearts and minds cohort.BMC medical ethics · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This interview study investigates the short- and long-term implications of incidental findings detected through brain imaging on research participants' lives and their surroundings. For this study, nine participants of the Rotterdam Scan Study with an incidental finding were approached and interviewed. When examining research participants' narratives on the impact of the disclosure of incidental findings, the authors identified five sets of tensions with regard to motivations for and expectations of research participation, preferences regarding disclosure, short- and long-term impacts and impacts on self and others. The paper shows: (1) that the impact of incidental findings may be greater than participants at first let on; (2) incidental findings can have significant effects on participants' social environment; and (3) participants may not feel prepared for disclosure even if incidental findings have been discussed during the informed consent process. The authors call for investigators to be aware of research participants' experiences and these short- and long-term impacts when designing suitable courses of action for the detection and management of incidental findings in research settings.
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Registered trials
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