ArticleGenome biology2020
The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication.
Article in Genome biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Plant sex chromosomes defy evolutionary models of expanding recombination suppression and genetic degeneration.Nature plants · 2021Pooled it
- Genomic architecture and evolution of heterostyly: new insights from Cordia subcordata (Boraginaceae).Molecular biology and evolution · 2026Article
- Domestication During Restoration: Unintentional Selection During Eight Generations of Wild Seed Propagation Reduces Herkogamy, Dichogamy and Heterozygosity in Clarkia pulchella.Molecular ecology · 2025Article
- Characterization and transcriptomic analysis provide novel insights into the sexual differentiation of the dioecious plant Bama Huoma (Cannabis sativa).BMC plant biology · 2025Article
- Rpv2 is part of a cluster of NLRs specific to Vitis rotundifolia and confers total resistance to grapevine downy mildew.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Seed Morphometry Reveals Two Major Groups in Spanish Grapevine Cultivars.Plants (Basel, Switzerland) · 2025Article
- Impacts of reproductive systems on grapevine genome and breeding.Nature communications · 2025Article
- Grapevine pangenome facilitates trait genetics and genomic breeding.Nature genetics · 2024Article
- Sexy ways: approaches to studying plant sex chromosomes.Journal of experimental botany · 2024Review
- Article
- High-quality genomes of Bombax ceiba and Ceiba pentandra provide insights into the evolution of Malvaceae species and differences in their natural fiber development.Plant communications · 2024Article
- Distinct structural variants and repeat landscape shape the genomes of the ancient grapes Aglianico and Falanghina.BMC plant biology · 2024Article
- Genealogical Analyses of 3 Cultivated and 1 Wild Specimen of Vitis vinifera from Greece.Genome biology and evolution · 2023Article
- Genetic insights into the dissolution of dioecy in diploid persimmon Diospyros oleifera Cheng.BMC plant biology · 2023Article
- Chromosome-level genome assembly of the endangered plant Tetraena mongolica.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023Article
- Evolution of sex in crops: recurrent scrap and rebuild.Breeding science · 2023Article
- Editorial: Growth regulation in horticultural plants: new insights in the omics era.Frontiers in plant science · 2023Article
- De novo whole-genome assembly in an interspecific hybrid table grape, 'Shine Muscat'.DNA research : an international journal for rapid publication of reports on genes and genomes · 2022Article
- Microstructure of Croatian Wild Grapevine (Plants (Basel, Switzerland) · 2022Article
- Labile sex expression in angiosperm species with sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
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Authors and funding
23 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA key step in domestication of the grapevine was the transition from separate sexes (dioecy) in wild Vitis vinifera ssp. sylvestris (V. sylvestris) to hermaphroditism in cultivated Vitis vinifera ssp. sativa (V. vinifera). It is known that V. sylvestris has an XY system and V. vinifera a modified Y haplotype (Yh) and that the sex locus is small, but it has not previously been precisely characterized.
resultsWe generate a high-quality de novo reference genome for V. sylvestris, onto which we map whole-genome re-sequencing data of a cross to locate the sex locus. Assembly of the full X, Y, and Yh haplotypes of V. sylvestris and V. vinifera sex locus and examining their gene content and expression profiles during flower development in wild and cultivated accessions show that truncation and deletion of tapetum and pollen development genes on the X haplotype likely causes male sterility, while the upregulation of a Y allele of a cytokinin regulator (APRT3) may cause female sterility. The downregulation of this cytokinin regulator in the Yh haplotype may be sufficient to trigger reversal to hermaphroditism. Molecular dating of X and Y haplotypes is consistent with the sex locus being as old as the Vitis genus, but the mechanism by which recombination was suppressed remains undetermined.
conclusionsWe describe the genomic and evolutionary characterization of the sex locus of cultivated and wild grapevine, providing a coherent model of sex determination in the latter and for transition from dioecy to hermaphroditism during domestication.
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