Evidence map›Paper›PMID 32892401›Full record

ReviewScandinavian journal of immunology2020

Macrophages and scavenger receptors in obesity-associated non-alcoholic liver fatty disease (NAFLD).

Sine Kragh Petersen, Orsolya Bilkei-Gorzo, Olivier Govaere, Anetta Härtlova

Open access · hybridAbstract readReview
In one paragraph

Review in Scandinavian journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Capsaicin: a spicy way in liver disease.Frontiers in pharmacology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sine Kragh PetersenDepartment of Microbiology and Immunology at Institute of Biomedicine, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Orsolya Bilkei-GorzoDepartment of Microbiology and Immunology at Institute of Biomedicine, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Olivier GovaereTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Anetta HärtlovaDepartment of Microbiology and Immunology at Institute of Biomedicine, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-8152-4361
University of Gothenburg · SENewcastle University · GB

Funding

Cancerfonden 19 0352 PjKnut och Alice Wallenbergs Stiftelse
6 · The paper itself

Abstract

With an increase in sedentary lifestyle and dietary over nutrition, obesity has become one of the major public health problems worldwide and is a prevalent predisposing risk factor to non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in Western developed countries. NAFLD represents a series of diseased states ranging from non-alcoholic fatty liver (NAFL) to steatohepatitis (NASH), which can lead to fibrosis and eventually to cirrhosis and hepatocellular carcinoma. Currently, the only effective treatment to cure end-stage liver disease is liver transplantation. Macrophages have been reported to play a crucial role in the progression of NAFLD, thereby are a potential target for therapy. In this review, we discuss the current knowledge on the role of macrophages and inflammatory signalling pathways associated with obesity and chronic liver inflammation, and their contribution to NAFLD development and progression.

Indexed as

Carcinoma, HepatocellularDisease ProgressionFatty LiverHumansLiver CirrhosisLiver NeoplasmsMacrophagesNon-alcoholic Fatty Liver DiseaseObesityReceptors, ScavengerReceptors, Scavengerlipid metabolismmacrophagesNAFLD

Identifiers

PMID32892401
PMCPMC7685160
OpenAlexW3083992107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.