Evidence map›Paper›PMID 32892309›Full record

ReviewEndocrine2021

Will

Luca Giovanella, Lorenzo Bacigalupo, Giorgio Treglia, Arnoldo Piccardo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 87 citations in OpenAlex.

  1. First-line [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. A novel imaging approach in hyperparathyroidism: [68Ga]Ga-Trivehexin PET/CT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. [European journal of nuclear medicine and molecular imaging · 2025
    Article
  10. Article
  11. Economic evaluation of [EJNMMI reports · 2025
    Article
  12. Japanese journal of radiology · 2025
    Article
  13. Article
  14. Article
  15. Comparison ofFrontiers in endocrinology · 2025
    Article
  16. Article
  17. Review
  18. Cost-effectiveness of one-stop-shop [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Luca GiovanellaClinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland. luca.giovanella@eoc.ch.ORCID http://orcid.org/0000-0003-0230-0974
Lorenzo BacigalupoDepartment of Diagnostic Imaging, Radiology and Nuclear Medicine, Ente Ospedaliero Galliera, Genova, Italy.
Giorgio TregliaClinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland.
Arnoldo PiccardoDepartment of Diagnostic Imaging, Radiology and Nuclear Medicine, Ente Ospedaliero Galliera, Genova, Italy.
Ente Ospedaliero Ospedali Galliera · ITEnte Ospedaliero Cantonale · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrimary hyperparathyroidism (PHPT) is a common endocrine disorder usually due to hyperfunctioning parathyroid glands (HPs). Surgical removal of the HPs is the main treatment for PHPT, making the correct detection and localization of HPs crucial to guiding targeted and minimally invasive surgical treatment in patients with PHPT. To date, different imaging methods have been used to detect and localize HPs, including radiology, nuclear medicine, and hybrid techniques.

methodsThe present work discusses the role and value of different imaging methods in PHPT and, particularly, evaluates the potential role of DISCUSSION: Cervical ultrasound (US) and parathyroid scintigraphy using

conclusionsDue to the excellent diagnostic performance of radiolabeled choline PET/CT and the low radiation burden, this technique seems to be an ideal candidate to substitute current imaging procedures including US, MIBI scintigraphy, 4D CT and MRI and perform a fast and reliable "one-stop-shop" preoperative localization of HP in patients with PHPT, including challenging cases of postoperative persistent/recurrent disease.

Indexed as

Hyperparathyroidism, PrimaryPositron Emission Tomography Computed TomographyCholineHumansParathyroid GlandsPositron-Emission TomographyTechnetium Tc 99m SestamibiCholinefluorocholineTechnetium Tc 99m SestamibiPositron emission tomographyPrimary hyperparathyroidismscintigraphyUltrasound

Identifiers

PMID32892309
OpenAlexW3083232992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.