ArticleWorld journal of surgery2020
Accurate Risk Stratification of Patients with Node-Positive Gastric Cancer by Lymph Node Ratio.
Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- The Lymph Node Ratio as a Predictive Biomarker for Individualized Benefit from Adjuvant Chemotherapy in Gastric Cancer: A Retrospective Cohort and Causal Machine Learning Study.Journal of gastrointestinal cancer · 2026Article
- Impact of self-expandable metallic prosthesis on lymph node dissemination in obstructive left-sided colorectal cancer.Surgical endoscopy · 2025Article
- Evaluation of three lymph node staging systems for prognostic prediction in gastric cancer: A systematic review and meta-analysis.World journal of gastrointestinal oncology · 2025Article
- Prognostic performance of examined lymph nodes, lymph node ratio, and positive lymph nodes in gastric cancer: a competing risk model study.Frontiers in endocrinology · 2025Article
- Clinicopathologic characteristics and predictive nomogram of skip lymph node metastasis in gastric cancer.Frontiers in oncology · 2025Article
- Prognostic significance of metastatic lymph node ratio in gastric cancer: a Western-center analysis.BMC surgery · 2023Article
- Evaluation of the prognostic value of negative to positive lymph node ratio in gastric cancer: results from multi-institutional cohorts from western and eastern datasets - Cohort study.Annals of medicine and surgery (2012) · 2023Article
- A novel nomogram based on the prognostic nutritional index for predicting postoperative outcomes in patients with stage I-III gastric cancer undergoing robotic radical gastrectomy.Frontiers in surgery · 2022Article
- Development and validation of lymph node ratio-based nomograms for primary duodenal adenocarcinoma after surgery.Frontiers in oncology · 2022Article
- Laparoscopic gastrectomy plus D2 lymphadenectomy is as effective as open surgery in terms of long-term survival: a single-institution study on gastric cancer.World journal of surgical oncology · 2021Article
- Clinical Influence of the Lymph Node Ratio on Lymph Node Metastasis-positive Gastric Cancer Patients Who Receive Curative Treatment.In vivo (Athens, Greece)Article
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Authors and funding
15 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to clarify the utility of lymph node ratio (LNR) for assessing the prognosis of patients with node-positive gastric cancer after curative gastrectomy.
methodsWe retrospectively analyzed data of 973 patients with node-positive gastric cancer who had undergone curative gastrectomy at nine institutions from 2010 to 2014. Survival analysis was performed by comparing LNR low and high groups according to the optimal cutoff value of LNR, which was determined using receiver operating characteristic curve analysis.
resultsLNR high was significantly associated with shorter disease-free survival and was an independent predictor of recurrence in all patients. Moreover, we obtained the similar results from analysis of each N stage. The prevalence of lymph node and peritoneal recurrence appeared to be higher in the LNR high group. Correlation analysis showed that LNR was negatively correlated with the number of retrieved nodes within every N stage; however, disease-free survival did not differ significantly between LNR low and high groups of each N stage with 16-30, 31-40, or >40 retrieved nodes.
conclusionsLNR is a strong prognostic factor and predictor of recurrence in patients with node-positive gastric cancer who have undergone curative gastrectomy. The combination of LNR and N staging permits more accurate prognostic stratification of patients with gastric cancer and may contribute to developing novel prognostic models.
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