ArticleDigestive diseases and sciences2021
Anemia Severity Associated with Increased Healthcare Utilization and Costs in Inflammatory Bowel Disease.
Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Risk factors of inflammatory bowel disease complicating anemia: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Hemoglobinometry at the point of care with activation of a hospital transfusion pathway versus usual care for the early detection of anaemia in primary care: the ANHEMOG randomized controlled trial.BMC primary care · 2026Trial
- The burden of anemia related to inflammatory bowel disease in China: Epidemic trends, subtype differences and driving factors.Journal of translational autoimmunity · 2026Article
- Machine learning prediction of increased healthcare utilization in colectomy for inflammatory bowel disease.International journal of colorectal disease · 2026Article
- Elevated preoperative red cell distribution width and incident anemia after metabolic and bariatric surgery: a cohort study.Frontiers in nutrition · 2026Article
- Article
- Predicting response to iron supplementation in patients with active inflammatory bowel disease (PRIme): a randomised trial protocol.BMJ open · 2024Article
- The hospitalization burden of inflammatory bowel disease in a southwestern highland region of China: a territory-wide study from 2015 to 2020.Frontiers in medicine · 2024Article
- Abdominal pain is associated with an increased risk of future healthcare resource utilization in inflammatory bowel disease.International journal of colorectal disease · 2023Article
- Symptoms associated with healthcare resource utilization in the setting of inflammatory bowel disease.Scientific reports · 2022Article
- Iron Deficiency Anemia: An Overlooked Complication of Crohn's Disease.Journal of hematology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnemia is a common systemic complication of inflammatory bowel disease (IBD) and is associated with worse disease outcomes, quality of life, and higher healthcare costs.
aimsThe purpose of this study was to determine how anemia severity impacts healthcare resource utilization and if treatment of anemia was associated with reduced utilization and costs.
methodsRetrospective chart review of adult patients managed by gastroenterology between 2014 and 2018 at a tertiary referral center.
resultsThe records of 1763 patients with IBD were included in the analysis, with 966 (55%) patients with CD, 799 (44%) with UC, and 18 (1%) with unspecified IBD. Of these patients, 951 (54%) had anemia. Patients with anemia had significantly more hospitalizations, increased length of stays, more ER, GI, and PCP visits, as well as higher costs when compared to patients with IBD without anemia. Patients with more severe anemia had more healthcare utilization and incurred even higher total costs. Treatment with IV or oral iron did not lower overall utilization or costs, when compared to patients with anemia who did not receive treatment (p < 0.0001).
conclusionsOur results demonstrate that the presence of anemia is correlated with increased resource utilization in patients with IBD, with increase in anemia severity associated with higher utilization and costs. Anemia has been associated with increased disease activity and could represent a marker of more severe disease, possibly explaining these associations. Our results suggest that treating anemia is associated with increased resource utilization; however, further research is needed to investigate this relationship.
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