Evidence map›Paper›PMID 32891737›Full record

ReviewInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Asymptomatic SARS Coronavirus 2 infection: Invisible yet invincible.

Lea A Nikolai, Christian G Meyer, Peter G Kremsner, Thirumalaisamy P Velavan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it, 232 citations in OpenAlex.

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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Lea A NikolaiInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Christian G MeyerInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Vietnamese-German Center for Medical Research, Hanoi, Viet Nam; Faculty of Medicine, Duy Tan University, Da Nang, Viet Nam.
Peter G KremsnerInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Centre de Recherches Medicales de Lambarene, Gabon.
Thirumalaisamy P VelavanInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Vietnamese-German Center for Medical Research, Hanoi, Viet Nam; Faculty of Medicine, Duy Tan University, Da Nang, Viet Nam. Electronic address: velavan@medizin.uni-tuebingen.de.
University of Tübingen · DECentre de Recherche Médicales de Lambaréné · GAVietnamese - German Center of Excellence in Medical Research · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While successful containment measures of COVID-19 in China and many European countries have led to flattened curves, case numbers are rising dramatically in other countries, with the emergence of a second wave expected. Asymptomatic individuals carrying SARS-CoV-2 are hidden drivers of the pandemic, and infectivity studies confirm the existence of transmission by asymptomatic individuals. The data addressed here show that characteristics of asymptomatic and presymptomatic infection are not identical. Younger age correlates strongly with asymptomatic and mild infections and children as hidden drivers. The estimated proportion of asymptomatic infections ranges from 18% to 81%. The current perception of asymptomatic infections does not provide clear guidance for public-health measures. Asymptomatic infections will be a key contributor in the spread of COVID-19. Asymptomatic cases should be reported in official COVID-19 statistics.

Indexed as

BetacoronavirusAdultAsymptomatic InfectionsChildCoronavirus InfectionsCOVID-19HumansImmunity, HerdMiddle AgedPandemicsPneumonia, ViralPublic HealthSARS-CoV-2AsymptomaticCase definitionCOVID-19Herd immunityPresymptomaticSARS-CoV-2

Identifiers

PMID32891737
PMCPMC7470698
OpenAlexW3082024381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.