Evidence map›Paper›PMID 32891117›Full record

ArticleBMC nephrology2020

An assessment of sensitivity biomarkers for urinary cadmium burden.

Yuting Li, Hongmei Wang, Jie Yu, Qiong Yan, Honggang Hu, Lishu Zhang, Tian Tian, Xianglei Peng, Shuo Yang, Shen Ke

Abstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuting LiDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Hongmei WangState Key Laboratory of Environmental Criteria and Risk Assessment, Department of Environment and Health, Chinese Research Academy of Environmental Sciences, Beijing, 100012, PR China. wanghmxj@163.com.
Jie YuDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Qiong YanDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Honggang HuDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Lishu ZhangDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Tian TianDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Xianglei PengDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Shuo YangDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China.
Shen KeDepartment of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, No.3, Shangyuan Village, Haidian District, Beijing, 100044, China. 8296@bjtu.edu.cn.

Funding

National Key Research and Development Program 2018YFC0213704Special Funds of the State Environmental Protection Public Welfare Industry 201309049
6 · The paper itself

Abstract

backgroundExcess cadmium (Cd) intake poses a general risk to health and to the kidneys in particular. Among indices of renal dysfunction under Cd burden measures are the urinary N-acetyl-β-D-glucosidase (UNAG) and urinary β

methodsTo ascertain the clinical benchmark dose of urinary Cd (UCd) burden for renal dysfunction, 1595 residents near a Cd site were surveyed. Urine was sampled and assayed. A benchmark dose low (BMDL) was obtained by fitting UCd levels and index levels.

resultsWe found that over 50% of the subjects were suffering from Cd exposure as their UCd levels far exceeded the national standard threshold of 5.000 μg/g creatinine (cr). Further analysis indicated that Uβ

conclusionsUβ

Indexed as

AcetylglucosaminidaseAgedbeta 2-MicroglobulinBiomarkersCadmiumEnvironmental ExposureFemaleHumansMaleMiddle AgedRenal InsufficiencyAcetylglucosaminidasebeta 2-MicroglobulinBiomarkersCadmiumBenchmark doseRenal dysfunctionUrinary cadmiumUrinary N-acetyl-β-D-glucosidase (UNAG)Urinary β2-microglobulin (Uβ2-MG)

Identifiers

PMID32891117
PMCPMC7487760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.