Evidence map›Paper›PMID 32891076›Full record

ArticleYeungnam University journal of medicine2021

Delayed treatment-free response after romiplostim discontinuation in pediatric chronic immune thrombocytopenia.

Hyun Ji Lim, Young Tae Lim, Jeong Ok Hah, Jae Min Lee

Open access · goldAbstract readCase Reports
In one paragraph

Article in Yeungnam University journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hyun Ji LimDepartment of Pediatrics, Yeungnam University Hospital, Daegu, Korea.
Young Tae LimDepartment of Pediatrics, Yeungnam University Hospital, Daegu, Korea.
Jeong Ok HahDepartment of Pediatrics, Daegu Fatima Hospital, Daegu, Korea.
Jae Min LeeDepartment of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
Yeungnam University Medical Center · KRDaegu Fatima Hospital · KRYeungnam University College

Funding

Yeungnam University
6 · The paper itself

Abstract

We report the case of a 16-month-old patient with chronic immune thrombocytopenia (ITP) patient who experienced delayed treatment-free response (TFR) after romiplostim treatment. He received intravenous immunoglobulin every month to maintain a platelet count above 20,000/μL for 2 years. Thereafter, he received rituximab and cyclosporine as second-line therapy, with no response, followed by romiplostim. After 4 weeks of treatment, the platelet count was maintained above 50,000/μL. Following 7 months of treatment, he discontinued romiplostim, and the platelet count decreased. His platelet counts remained above 50,000/μL, without any bleeding symptoms, 2 years after romiplostim discontinuation. This is the first report of TFR after romiplostim treatment in pediatric chronic ITP.

Indexed as

ChildImmune thrombocytopenia, Idiopathic thrombocytopenic purpuraRomiplostimTreatment-free response

Identifiers

PMID32891076
PMCPMC8016626
OpenAlexW3047896951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.